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Andrew D Redfern

Explore the profile of Andrew D Redfern including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 871
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Recent Articles
1.
Emmett L, Subramaniam S, Crumbaker M, Joshua A, Sandhu S, Nguyen A, et al.
Lancet Oncol . 2025 Feb; 26(3):291-299. PMID: 39956124
Background: Interim analysis of the ENZA-p trial showed improved prostate-specific antigen (PSA) progression-free survival with the addition of lutetium-177 [Lu]Lu-prostate-specific membrane antigen (PSMA)-617 to enzalutamide as first-line treatment of metastatic...
2.
Chi L, Redfern A, Lim Kam Sian T, Street I, Burrows A, Roslan S, et al.
Int J Mol Sci . 2024 Sep; 25(17). PMID: 39273106
We reported previously that in preclinical models, BMP4 is a potent inhibitor of breast cancer metastasis and that high BMP4 protein levels predict favourable patient outcomes. Here, we analysed a...
3.
Crespo-Garcia C, Campbell J, Taaffe D, Peddle-McIntyre C, Jeffery E, Galvao D, et al.
Exerc Immunol Rev . 2024 Aug; 30:26-48. PMID: 39094178
Conventional chemotherapies can stimulate the immune system by increasing tumour antigenicity (e.g., neoantigen exposure to immune cells) and altering adjuvanticity in the tumour (e.g., danger associated molecular patterns and cytokines)....
4.
Kim J, Taaffe D, Galvao D, Clay T, Redfern A, Gray E, et al.
BMC Cancer . 2024 Jul; 24(1):784. PMID: 38951803
Introduction: Physical activity is associated with improved disease progression and cancer-specific survival in patients with prostate cancer (PCa). However, the mechanisms underlying these associations remain unclear, while the relative impact...
5.
Chi L, Redfern A, Roslan S, Street I, Burrows A, Anderson R
Cell Commun Signal . 2024 Apr; 22(1):248. PMID: 38689334
Background: Bone morphogenetic protein 4 (BMP4) is a potent inhibitor of breast cancer metastasis. However, a tumor-promoting effect of BMP4 is reported in other tumor types, especially when SMAD4 is...
6.
Emmett L, Subramaniam S, Crumbaker M, Nguyen A, Joshua A, Weickhardt A, et al.
Lancet Oncol . 2024 Apr; 25(5):563-571. PMID: 38621400
Background: Enzalutamide and lutetium-177 [Lu]Lu-prostate-specific membrane antigen (PSMA)-617 both improve overall survival in patients with metastatic castration-resistant prostate cancer. Androgen and PSMA receptors have a close intracellular relationship, with data...
7.
Hayne D, Ong K, Swarbrick N, McCombie S, Moe A, Hawks C, et al.
BJU Int . 2024 Mar; 134(2):283-290. PMID: 38469652
Objectives: To assess the safety of sub-urothelial injection of durvalumab and examine the impact on tissue and circulating immune cell populations. Patients And Methods: The patients were chemotherapy and immunotherapy...
8.
Hofman M, Emmett L, Sandhu S, Iravani A, Buteau J, Joshua A, et al.
Lancet Oncol . 2023 Dec; 25(1):99-107. PMID: 38043558
Background: The TheraP study reported improved prostate-specific antigen responses with lutetium-177 [Lu]Lu-PSMA-617 versus cabazitaxel in men with metastatic castration-resistant prostate cancer progressing after docetaxel. In this Article, we report the...
9.
Kim J, Taaffe D, Galvao D, Clay T, Redfern A, Hart N, et al.
Prostate Cancer Prostatic Dis . 2022 Nov; 26(4):795-801. PMID: 36446945
Purpose: Although skeletal muscle releases cytokines called myokines during exercise, the kinetics of the acute myokine response to exercise (exercise-induced circulatory myokine level alteration) is unknown in patients with advanced...
10.
Al-Zubaidi M, Viswambaram P, McCombie S, Liow E, Lenzo N, Ferguson T, et al.
BMJ Open . 2022 Apr; 12(4):e060478. PMID: 35428649
Introduction: Bladder cancer is a lethal disease with a rising incidence on a background of limited conventional imaging modalities for staging (either CT of the chest-abdomen-pelvis or 18F-fluorodeoxyglucose positron emitting...