Shancy Petsel Jacob
Overview
Explore the profile of Shancy Petsel Jacob including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
102
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0
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Recent Articles
1.
Abhilasha K, Sumanth M, Chaithra V, Jacob S, Thyagarajan A, Sahu R, et al.
Free Radic Biol Med
. 2019 Aug;
143:275-287.
PMID: 31442556
Platelet-activating factor (PAF) is a potent inflammatory agonist. In Swiss albino mice, intraperitoneal injection of PAF causes sudden death with oxidative stress and disseminated intravascular coagulation (DIC), characterized by prolonged...
2.
Sumanth M, Abhilasha K, Jacob S, Chaithra V, Basrur V, Willard B, et al.
Immunobiology
. 2019 Jun;
224(5):672-680.
PMID: 31239174
Alpha-1-acid glycoprotein (AGP-1) is a major positive acute phase glycoprotein with unknown functions that likely play a role in inflammation. We tested its involvement in a variety of inflammatory responses...
3.
Chaithra V, Jacob S, Lakshmikanth C, Sumanth M, Abhilasha K, Chen C, et al.
J Lipid Res
. 2018 Aug;
59(11):2063-2074.
PMID: 30139761
Platelet-activating factor (PAF) is a potent inflammatory mediator that exerts its actions via the single PAF receptor (PAF-R). Cells that biosynthesize alkyl-PAF also make abundant amounts of the less potent...
4.
Lakshmikanth C, Jacob S, Kudva A, Latchoumycandane C, Yashaswini P, Sumanth M, et al.
Sci Rep
. 2016 Oct;
6:34666.
PMID: 27698491
The endotoxin lipopolysaccharide (LPS) promotes sepsis, but bacterial peptides also promote inflammation leading to sepsis. We found, intraperitoneal administration of live or heat inactivated E. coli JE5505 lacking the abundant...
5.
Jacob S, Lakshmikanth C, Chaithra V, Kumari T, Chen C, McIntyre T, et al.
PLoS One
. 2016 Apr;
11(4):e0153282.
PMID: 27064683
Lipopolysaccharide (LPS) signaling through Toll-like receptor-4 (TLR-4) has been implicated in the pathogenesis of many infectious diseases. Some believe that TLR-mediated pathogenicity is due, in part, to the lipid pro-inflammatory...
6.
Lakshmikanth C, Jacob S, Chaithra V, de Castro-Faria-Neto H, Marathe G
Inflamm Res
. 2016 Mar;
65(8):587-602.
PMID: 26995266
Introduction: Sepsis is a complex inflammatory disorder believed to originate from an infection by any types of microbes and/or their products. It is the leading cause of death in intensive...
7.
Marathe G, Pandit C, Lakshmikanth C, Chaithra V, Jacob S, DSouza C
J Lipid Res
. 2014 May;
55(9):1847-54.
PMID: 24859738
Mounting ambiguity persists around the functional role of the plasma form of platelet-activating factor acetylhydrolase (PAF-AH). Because PAF-AH hydrolyzes PAF and related oxidized phospholipids, it is widely accepted as an...