Seungwan Hong
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Explore the profile of Seungwan Hong including associated specialties, affiliations and a list of published articles.
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8
Citations
39
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Recent Articles
1.
Hong S, Walker C, Choi Y, Gursoy G
Nat Commun
. 2025 Mar;
16(1):2380.
PMID: 40064866
Next generation sequencing reads from RNA-seq studies expose private genotypes of individuals during computation. Here, we introduce pQuant, an algorithm that employs homomorphic encryption to ensure privacy-preserving quantification of gene...
2.
Blindenbach J, Kang J, Hong S, Karam C, Lehner T, Gursoy G
Genome Biol
. 2024 Dec;
25(1):314.
PMID: 39696687
Cloud computing allows storing the ever-growing genotype-phenotype datasets crucial for precision medicine. Due to the sensitive nature of this data and varied laws and regulations, additional security measures are needed...
3.
Hong S, Choi Y, Joo D, Gursoy G
J Biomed Inform
. 2024 Jun;
156:104678.
PMID: 38936565
Objective: Linear and logistic regression are widely used statistical techniques in population genetics for analyzing genetic data and uncovering patterns and associations in large genetic datasets, such as identifying genetic...
4.
Blindenbach J, Kang J, Hong S, Karam C, Lehner T, Gursoy G
bioRxiv
. 2024 May;
PMID: 38695012
Cloud computing provides the opportunity to store the ever-growing genotype-phenotype data sets needed to achieve the full potential of precision medicine. However, due to the sensitive nature of this data...
5.
Park C, John H, Lee J, Hong S, Kim M, Park S, et al.
Medicine (Baltimore)
. 2022 Sep;
101(35):e30208.
PMID: 36107606
Postherpetic neuralgia (PHN) is the most common complication of herpes zoster, whereas postherpetic pruritus (PHP) a rare one. Although PHN has been extensively studied, few studies have investigated PHP. The...
6.
Hong S, Park J, Cho W, Choe H, Cheon J
BMC Genomics
. 2022 Apr;
23(1):284.
PMID: 35395714
Background: Disclosure of patients' genetic information in the process of applying machine learning techniques for tumor classification hinders the privacy of personal information. Homomorphic Encryption (HE), which supports operations between...
7.
Kim M, Harmanci A, Bossuat J, Carpov S, Cheon J, Chillotti I, et al.
Cell Syst
. 2021 Aug;
12(11):1108-1120.e4.
PMID: 34464590
Genotype imputation is a fundamental step in genomic data analysis, where missing variant genotypes are predicted using the existing genotypes of nearby "tag" variants. Although researchers can outsource genotype imputation,...
8.
Kim D, Son Y, Kim D, Kim A, Hong S, Cheon J
BMC Med Genomics
. 2020 Jul;
13(Suppl 7):77.
PMID: 32693801
Background: One of three tasks in a secure genome analysis competition called iDASH 2018 was to develop a solution for privacy-preserving GWAS computation based on homomorphic encryption. The scenario is...
9.
Park S, Kim M, Seo S, Hong S, Han K, Lee K, et al.
BMC Genomics
. 2019 Apr;
20(Suppl 2):188.
PMID: 30967116
Background: Single Nucleotide Polymorphism (SNP) in the genome has become crucial information for clinical use. For example, the targeted cancer therapy is primarily based on the information which clinically important...