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Seung-Wook Ryu

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Articles 33
Citations 1203
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Recent Articles
11.
Yim N, Ryu S, Han E, Yoon J, Choi K, Choi C
PLoS One . 2014 Jun; 9(6):e99937. PMID: 24941066
Mutant ubiquitin UBB+1 is observed in a variety of aging-related neurodegenerative diseases and acts as a potent inhibitor of the ubiquitin proteasome system (UPS). In the present study, we investigated...
12.
Kim T, Park Y, Ryu S, Kim D, Park J, Park J
Allergy Asthma Immunol Res . 2014 Mar; 6(2):163-8. PMID: 24587954
Purpose: Asthma is a pulmonary chronic inflammatory disease characterized by airway obstruction and hyperresponsiveness. Pattern recognition receptors are known to play a key role in the development of allergic diseases...
13.
Han E, Lee J, Ryu S, Choi C
Biochem Biophys Res Commun . 2014 Jan; 443(4):1218-25. PMID: 24388986
Gr-1(+)CD11b(+) cells can suppress innate and adaptive immunity, and the functional immunosuppressive characteristics of these cells can be modulated by the tumor microenvironment. Since Gr-1(+)CD11(+) cells are also involved in...
14.
Fogel A, Dlouhy B, Wang C, Ryu S, Neutzner A, Hasson S, et al.
Mol Cell Biol . 2013 Jul; 33(18):3675-88. PMID: 23878393
During autophagy, a double membrane envelops cellular material for trafficking to the lysosome. Human beclin-1 and its yeast homologue, Atg6/Vps30, are scaffold proteins bound in a lipid kinase complex with...
15.
Min J, Jang J, Keum D, Ryu S, Choi C, Jeong K, et al.
Sci Rep . 2013 Jun; 3:2075. PMID: 23797902
Structured illumination microscopy (SIM) breaks the optical diffraction limit by illuminating a sample with a series of line-patterned light. Recently, in order to alleviate the requirement of precise knowledge of...
16.
Ryu S, Yoon J, Yim N, Choi K, Choi C
PLoS One . 2013 May; 8(5):e63495. PMID: 23658835
Transforming growth factor-β signaling is known to be a key signaling pathway in the induction of epithelial-mesenchymal transition. However, the mechanism of TGF-β signaling in the modulation of EMT remains...
17.
Yeon J, Na D, Choi K, Ryu S, Choi C, Park J
Biomed Microdevices . 2012 Jul; 14(6):1141-8. PMID: 22821236
Since most of the bioavailable drugs are impermeable through the blood-brain barrier (BBB), development of a rapid and reliable permeability assay system has been a challenge in drug discovery targeting...
18.
Kim S, Kwon M, Ryu M, Chung H, Tadi S, Kim Y, et al.
Cell Metab . 2012 Jul; 16(2):274-83. PMID: 22819524
Although substantial progress has been made in understanding the mechanisms underlying the expression of mtDNA-encoded polypeptides, the regulatory factors involved in mitoribosome-mediated synthesis and simultaneous insertion of mitochondrial oxidative phosphorylation...
19.
Choi K, Lee K, Ryu S, Im M, Kook K, Choi C
Mol Vis . 2012 May; 18:1010-20. PMID: 22550395
Purpose: Transforming growth factor-β (TGF-β) plays a key role in transforming retinal pigment epithelial (RPE) cells into mesenchymal fibroblastic cells, which are implicated in proliferative vitreoretinopathy. Herein, we tested the...
20.
Ryu S, Choi K, Park J, Park Y, Kim S, Choi C
Cancer Lett . 2012 Apr; 323(1):62-68. PMID: 22484496
Mitochondrial fusion and fission are dynamically regulated during apoptotic cell death, and mitofusin (Mfn) and related proteins have been shown to be involved in apoptosis-associated changes in mitochondrial morphology and...