Seth Rakoff-Nahoum
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Explore the profile of Seth Rakoff-Nahoum including associated specialties, affiliations and a list of published articles.
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37
Citations
4647
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Recent Articles
1.
Kuziel G, Lozano G, Simian C, Li L, Manion J, Stephen-Victor E, et al.
Cell
. 2025 Mar;
PMID: 40056901
Plants are composed of diverse secondary metabolites (PSMs), which are widely associated with human health. Whether and how the gut microbiome mediates such impacts of PSMs is poorly understood. Here,...
2.
Stephen-Victor E, Kuziel G, Martinez-Blanco M, Jugder B, Benamar M, Wang Z, et al.
Nature
. 2025 Jan;
638(8051):760-768.
PMID: 39843735
Tolerance to dietary antigens is critical for avoiding deleterious type 2 immune responses resulting in food allergy (FA) and anaphylaxis. However, the mechanisms resulting in both the maintenance and failure...
3.
Arthur C, Hollenhorst M, Wu S, Jajosky R, Nakahara H, Jan H, et al.
Semin Immunol
. 2024 Oct;
74-75:101892.
PMID: 39405833
ABO blood group antigens, which are complex carbohydrate moieties, and the first human polymorphisms identified, are critical in transfusion medicine and transplantation. Despite their discovery over a century ago, significant...
4.
Prochera A, Muppirala A, Kuziel G, Soualhi S, Shepherd A, Sun L, et al.
bioRxiv
. 2024 Apr;
PMID: 38659931
Glial cells of the enteric nervous system (ENS) interact closely with the intestinal epithelium and secrete signals that influence epithelial cell proliferation and barrier formation . Whether these interactions are...
5.
Jan H, Wu S, Stowell C, Vallecillo-Zuniga M, Paul A, Patel K, et al.
Mol Cell Proteomics
. 2024 Mar;
23(5):100747.
PMID: 38490531
Although immune tolerance evolved to reduce reactivity with self, it creates a gap in the adaptive immune response against microbes that decorate themselves in self-like antigens. This is particularly apparent...
6.
Mills K, Albert B, Bechard L, Chu S, Duggan C, Kaza A, et al.
Pediatr Crit Care Med
. 2024 Jan;
25(2):118-127.
PMID: 38240536
Objectives: The routine use of stress ulcer prophylaxis (SUP) in infants with congenital heart disease (CHD) in the cardiac ICU (CICU) is controversial. We aimed to conduct a pilot study...
7.
Manion J, Musser M, Kuziel G, Liu M, Shepherd A, Wang S, et al.
Nature
. 2023 Sep;
622(7983):611-618.
PMID: 37699522
Clostridioides difficile infection (CDI) is a major cause of healthcare-associated gastrointestinal infections. The exaggerated colonic inflammation caused by C. difficile toxins such as toxin B (TcdB) damages tissues and promotes...
8.
Jenkins D, Woolston B, Hood-Pishchany M, Pelayo P, Konopaski A, Peters M, et al.
Nat Microbiol
. 2023 Aug;
8(9):1641-1652.
PMID: 37563289
The human vaginal microbiota is frequently dominated by lactobacilli and transition to a more diverse community of anaerobic microbes is associated with health risks. Glycogen released by lysed epithelial cells...
9.
Wu S, Arthur C, Jan H, Garcia-Beltran W, Patel K, Rathgeber M, et al.
Blood
. 2023 Jun;
142(8):742-747.
PMID: 37367252
Among the risk factors for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), ABO(H) blood group antigens are among the most recognized predictors of infection. However, the mechanisms by which ABO(H)...
10.
Mahajan G, Doherty E, To T, Sutherland A, Grant J, Junaid A, et al.
Microbiome
. 2022 Nov;
10(1):201.
PMID: 36434666
Background: A dominance of non-iners Lactobacillus species in the vaginal microbiome is optimal and strongly associated with gynecological and obstetric health, while the presence of diverse obligate or facultative anaerobic...