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Gavin A Kuziel

Explore the profile of Gavin A Kuziel including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 89
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Recent Articles
1.
Kuziel G, Lozano G, Simian C, Li L, Manion J, Stephen-Victor E, et al.
Cell . 2025 Mar; PMID: 40056901
Plants are composed of diverse secondary metabolites (PSMs), which are widely associated with human health. Whether and how the gut microbiome mediates such impacts of PSMs is poorly understood. Here,...
2.
Stephen-Victor E, Kuziel G, Martinez-Blanco M, Jugder B, Benamar M, Wang Z, et al.
Nature . 2025 Jan; 638(8051):760-768. PMID: 39843735
Tolerance to dietary antigens is critical for avoiding deleterious type 2 immune responses resulting in food allergy (FA) and anaphylaxis. However, the mechanisms resulting in both the maintenance and failure...
3.
Prochera A, Muppirala A, Kuziel G, Soualhi S, Shepherd A, Sun L, et al.
bioRxiv . 2024 Apr; PMID: 38659931
Glial cells of the enteric nervous system (ENS) interact closely with the intestinal epithelium and secrete signals that influence epithelial cell proliferation and barrier formation . Whether these interactions are...
4.
Manion J, Musser M, Kuziel G, Liu M, Shepherd A, Wang S, et al.
Nature . 2023 Sep; 622(7983):611-618. PMID: 37699522
Clostridioides difficile infection (CDI) is a major cause of healthcare-associated gastrointestinal infections. The exaggerated colonic inflammation caused by C. difficile toxins such as toxin B (TcdB) damages tissues and promotes...
5.
Kuziel G, Rakoff-Nahoum S
Curr Biol . 2022 Mar; 32(6):R257-R264. PMID: 35349808
All animals, from cnidarians to humans, are colonized with microbes, and the greatest diversity and magnitude of these host-associated microorganisms resides within the intestine. Referred to as the gut microbiome,...
6.
Park S, Rao C, Coyte K, Kuziel G, Zhang Y, Huang W, et al.
Cell . 2022 Feb; 185(3):513-529.e21. PMID: 35120663
The human gut microbiota resides within a diverse chemical environment challenging our ability to understand the forces shaping this ecosystem. Here, we reveal that fitness of the Bacteroidales, the dominant...