Sergio F Sousa
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Explore the profile of Sergio F Sousa including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Soares R, Azevedo L, Vasconcelos V, Pratas D, Sousa S, Carneiro J
J Chem Inf Model
. 2024 Nov;
64(24):9576-9593.
PMID: 39602490
Cyanobacteria strains have the potential to produce bioactive compounds that can be used in therapeutics and bioremediation. Therefore, compiling all information about these compounds to consider their value as bioresources...
2.
Fernandes S, Sousa M, Martins F, Simoes M, Sousa S
STAR Protoc
. 2024 Oct;
5(4):103367.
PMID: 39378154
The search and development of new quorum-sensing (QS) inhibitors are ongoing processes for biofilm control. Here, we present a protocol for in silico characterization of natural-based molecules as QS inhibitors....
3.
Paquete-Ferreira J, Freire F, Fernandes H, Muthukumaran J, Ramos J, Bryton J, et al.
Front Chem
. 2024 Aug;
12:1379914.
PMID: 39170866
The rise of antibiotic-resistant bacterial strains has become a critical health concern. According to the World Health Organization, the market introduction of new antibiotics is alarmingly sparse, underscoring the need...
4.
Batista-Silva J, Gomes D, Sousa S, Sousa A, Passarinha L
Drug Discov Today
. 2024 Aug;
29(9):104130.
PMID: 39103143
Prostate cancer (PCa) is one of the leading cancers in men and the lack of suitable biomarkers or their modulators results in poor prognosis. Membrane proteins (MPs) have a crucial...
5.
Zeghbib W, Boudjouan F, Carneiro J, Oliveira A, Sousa S, Pintado M, et al.
Food Chem
. 2024 Jul;
460(Pt 1):140414.
PMID: 39084103
Opuntia plants are abundant but still underexplored edible resources of the Algerian region. This work chemically characterizes extracts of different parts of the fruit of the commercial Opuntia ficus-indica (L.)...
6.
Thakur C, Martins F, Karthikeyan C, Bhal S, Kundu C, Moorthy N, et al.
J Mol Model
. 2024 Jul;
30(8):261.
PMID: 38985223
Context: Multiwalled carbon nanotubes (MWCNTs) functionalized with lysine via 1,3-dipolar cycloaddition and conjugated to galactose or mannose are potential nanocarriers that can effectively bind to the lectin receptor in MDA-MB-231...
7.
Mendes F, Santos-Pereira C, Vieira T, Martins Pinto M, Castro B, Sousa S, et al.
FEBS Lett
. 2024 May;
598(13):1655-1666.
PMID: 38750637
Cymoxanil (CYM) is a widely used synthetic acetamide fungicide, but its biochemical mode of action remains elusive. Since CYM inhibits cell growth, biomass production, and respiration in Saccharomyces cerevisiae, we...
8.
Sousa J, Santos-Pereira C, Gomes J, Costa A, Santos A, Franco-Duarte R, et al.
Appl Microbiol Biotechnol
. 2024 May;
108(1):329.
PMID: 38727750
Xylanases are key biocatalysts in the degradation of the β-1,4-glycosidic linkages in the xylan backbone of hemicellulose. These enzymes are potentially applied in a wide range of bioprocessing industries under...
9.
Leitao M, Vieira T, Sousa S, Borges F, Simoes M, Borges A
Microb Pathog
. 2024 Apr;
191:106663.
PMID: 38679246
Quorum sensing (QS) has a central role in biofilm lifestyle and antimicrobial resistance, and disrupting these signaling pathways is a promising strategy to control bacterial pathogenicity and virulence. In this...
10.
Vieira T, Leitao M, Cerqueira N, Sousa S, Borges A, Simoes M
J Appl Microbiol
. 2024 Apr;
135(5).
PMID: 38587815
Aims: Drug repurposing is an attractive strategy to control biofilm-related infectious diseases. In this study, two drugs (montelukast and cefoperazone) with well-established therapeutic applications were tested on Pseudomonas aeruginosa quorum...