Pedro A Fernandes
Overview
Explore the profile of Pedro A Fernandes including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
182
Citations
1990
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
da Silva J, Castro-Amorim J, Mukherjee A, Ramos M, Fernandes P
Expert Opin Drug Discov
. 2025 Feb;
:1-19.
PMID: 40012249
Introduction: Snake venom is a rich source of toxins with great potential for therapeutic applications. In addition to its efficacy in treating hypertension, acute coronary syndrome, and other heart conditions,...
2.
da Silva J, Ramos M, Fernandes P
Biochimie
. 2025 Jan;
PMID: 39800211
This study focuses on the quaternary structure of the viper-secreted phospholipase A (PLA), a central toxin in viper envenomation. PLA enzymes catalyze the hydrolysis of the sn-2 ester bond of...
3.
Castro-Amorim J, Pinto A, Mukherjee A, Ramos M, Fernandes P
Chem Sci
. 2025 Jan;
16(4):1974-1985.
PMID: 39759936
Snake venom-secreted phospholipases A (svPLAs) are critical, highly toxic enzymes present in almost all snake venoms. Upon snakebite envenomation, svPLAs hydrolyze cell membrane phospholipids and induce pathological effects such as...
4.
Radman K, Crnolatac I, Bregovic N, Jelic Matosevic Z, Fernandes P, Merunka D, et al.
Int J Biol Macromol
. 2024 Dec;
290:138828.
PMID: 39701257
Streptococcus mutans, a bacterium commonly found in the human oral cavity, is considered the primary causative agent of dental caries. A key player in the pathophysiology of S. mutans is...
5.
Rotilio L, Bayer T, Meinert H, Teixeira L, Johansen M, Sommerfeldt A, et al.
Angew Chem Int Ed Engl
. 2024 Nov;
64(7):e202419535.
PMID: 39611359
Global plastic production exceeded 400 million tons in 2022, urgently demanding improved waste management and recycling strategies for a circular plastic economy. While the enzymatic hydrolysis of polyethylene terephthalate (PET)...
6.
S Coimbra J, Gissler A, Nitor E, Rostamipour K, Cunha A, Ramos M, et al.
JACS Au
. 2024 Nov;
4(11):4295-4306.
PMID: 39610721
Snakebite envenoming claims 81-138 thousand lives annually, with vipers responsible for many of those. Phospholipase A (PLA) enzymes and PLA-like proteins are among the most important viper venom toxins. The...
7.
T Magalhaes B, S Coimbra J, M Silva R, Ferreira M, S Santos R, Gameiro P, et al.
Biochemistry
. 2024 Nov;
63(24):3381-3394.
PMID: 39571107
Nucleic acid mimics (NAMs) have demonstrated high potential as antibacterial drugs. However, very few studies have assessed their possible diffusion across the bacterial envelope. In this work, we studied NAMs'...
8.
Gusenda C, Calixto A, da Silva J, Fernandes P, Grininger M
Angew Chem Int Ed Engl
. 2024 Nov;
64(2):e202412195.
PMID: 39526922
Fatty acid synthase (FAS) multienzymes are responsible for de novo fatty acid biosynthesis and crucial in primary metabolism. Despite extensive research, the molecular details of the FAS catalytic mechanisms are...
9.
Sousa J, Ramos M, Fernandes P
J Phys Chem B
. 2024 Aug;
128(39):9447-9454.
PMID: 39185757
We have studied the hydroxylation mechanism of l-Tyr by the heme-dependent enzyme CYP76AD1 from the sugar beet (). This enzyme has a promising biotechnological application in modified yeast strains to...
10.
Pinto A, Ferreira P, Cunha A, Havenith R, Magalhaes A, Ramos M, et al.
Chem Sci
. 2024 Jun;
15(25):9793-9805.
PMID: 38939148
Secreted phospholipase A2 (sPLA2) is a Ca-dependent, widely distributed enzyme superfamily in almost all mammalian tissues and bacteria. It is also a critical component of the venom of nearly all...