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Sergio Bondanza

Explore the profile of Sergio Bondanza including associated specialties, affiliations and a list of published articles. Areas
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Articles 20
Citations 629
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Recent Articles
1.
Dellambra E, Cordisco S, Monache F, Bondanza S, Teson M, Nicodemi E, et al.
Orphanet J Rare Dis . 2022 Jul; 17(1):275. PMID: 35854363
Background: Secreted R-spondin (RSPO) proteins play a key role in reproductive organ development, epithelial stem cell renewal and cancer induction by reinforcing canonical Wnt signaling. We have previously reported that...
2.
Enzo E, Cattaneo C, Consiglio F, Polito M, Bondanza S, De Luca M
Methods Cell Biol . 2022 Jul; 170:101-116. PMID: 35811094
Regenerative medicine has its roots in harnessing stem cells for permanent restoration of damaged or diseased tissues. The first procedure for the transplantation of epidermal cultures in massive full-thickness burns...
3.
Enzo E, Secone Seconetti A, Forcato M, Tenedini E, Polito M, Sala I, et al.
Nat Commun . 2021 May; 12(1):2505. PMID: 33947848
Autologous epidermal cultures restore a functional epidermis on burned patients. Transgenic epidermal grafts do so also in genetic skin diseases such as Junctional Epidermolysis Bullosa. Clinical success strictly requires an...
4.
De Rosa L, Latella M, Secone Seconetti A, Cattelani C, Bauer J, Bondanza S, et al.
Cold Spring Harb Perspect Biol . 2019 Oct; 12(5). PMID: 31653644
To date, more than 200 monogenic, often devastating, skin diseases have been described. Because of unmet medical needs, development of long-lasting and curative therapies has been consistently attempted, with the...
5.
Hirsch T, Rothoeft T, Teig N, Bauer J, Pellegrini G, De Rosa L, et al.
Nature . 2017 Nov; 551(7680):327-332. PMID: 29144448
Junctional epidermolysis bullosa (JEB) is a severe and often lethal genetic disease caused by mutations in genes encoding the basement membrane component laminin-332. Surviving patients with JEB develop chronic wounds...
6.
Bauer J, Koller J, Murauer E, De Rosa L, Enzo E, Carulli S, et al.
J Invest Dermatol . 2016 Nov; 137(3):778-781. PMID: 27840234
No abstract available.
7.
Maurelli R, Tinaburri L, Gangi F, Bondanza S, Severi A, Scarponi C, et al.
J Cell Sci . 2016 Jan; 129(5):1003-17. PMID: 26795563
The role of Ras in human skin tumorigenesis induction is still ambiguous. Overexpression of oncogenic Ras causes premature senescence in cultured human cells and hyperplasia in transgenic mice. Here, we...
8.
Levati L, Pagani E, Romani S, Castiglia D, Piccinni E, Covaciu C, et al.
Pigment Cell Melanoma Res . 2011 Apr; 24(3):538-50. PMID: 21466664
The SKI protein is a transcriptional coregulator over-expressed in melanoma. Experimentally induced down-regulation of SKI inhibits melanoma cell growth in vitro and in vivo. MicroRNAs (miRNAs) negatively modulate gene expression...
9.
Cordisco S, Maurelli R, Bondanza S, Stefanini M, Zambruno G, Guerra L, et al.
J Invest Dermatol . 2009 Nov; 130(4):1048-62. PMID: 19907431
Accumulation of senescent cells contributes to the reduced regenerative capacity in aged tissues. By evaluating the molecular pathways of senescence in relation to proliferative potential of primary keratinocyte cultures from...
10.
Levati L, Alvino E, Pagani E, Arcelli D, Caporaso P, Bondanza S, et al.
Int J Oncol . 2009 Jul; 35(2):393-400. PMID: 19578755
Altered expression of microRNAs (miRNAs) has been detected in cancer, suggesting that these small non-coding RNAs can act as oncogenes or tumor suppressor genes. In the present study, we investigated...