Elena Enzo
Overview
Explore the profile of Elena Enzo including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
5073
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Recent Articles
1.
Polito M, Romaldini A, Tagliazucchi L, Marini G, Radice F, Gozza G, et al.
Biol Direct
. 2024 Oct;
19(1):91.
PMID: 39396994
The complex network governing self-renewal in epidermal stem cells (EPSCs) is only partially defined. FOXM1 is one of the main players in this network, but the upstream signals regulating its...
2.
Sercia L, Romano O, Marini G, Enzo E, Forcato M, De Rosa L, et al.
Mol Ther Methods Clin Dev
. 2024 Sep;
32(3):101311.
PMID: 39234443
Lamellar ichthyosis (LI) is a chronic disease, mostly caused by mutations in the gene, marked by impaired skin barrier formation. No definitive therapies are available, and current treatments aim at...
3.
Carretta C, Parenti S, Bertesi M, Rontauroli S, Badii F, Tavernari L, et al.
Leukemia
. 2024 Aug;
38(10):2171-2182.
PMID: 39179669
JAK2V617F is the most recurrent genetic mutation in Philadelphia-negative chronic Myeloproliferative Neoplasms (MPNs). Since the JAK2 locus is located on Chromosome 9, we hypothesized that Chromosome 9 copy number abnormalities...
4.
Coordinating energy metabolism and signaling pathways in epithelial self-renewal and differentiation
Polito M, Romaldini A, Rinaldo S, Enzo E
Biol Direct
. 2024 Aug;
19(1):63.
PMID: 39113077
Epidermal stem cells (EPSCs) are essential for maintaining skin homeostasis and ensuring a proper wound healing. During in vitro cultivations, EPSCs give rise to transient amplifying progenitors and differentiated cells,...
5.
Polito M, Marini G, Fabrizi A, Sercia L, Enzo E, De Luca M
Cell Death Dis
. 2024 Jul;
15(7):508.
PMID: 39019868
Epidermal stem cells orchestrate epidermal renewal and timely wound repair through a tight regulation of self-renewal, proliferation, and differentiation. In culture, human epidermal stem cells generate a clonal type referred...
6.
Cuoghi S, Caraffi R, Anderlini A, Baraldi C, Enzo E, Vandelli M, et al.
Wiley Interdiscip Rev Nanomed Nanobiotechnol
. 2024 Jul;
16(4):e1979.
PMID: 38955512
Enzyme-based therapy has garnered significant attention for its current applications in various diseases. Despite the notable advantages associated with the use of enzymes as therapeutic agents, that could have high...
7.
Rosignoli S, Lustrino E, Conci A, Fabrizi A, Rinaldo S, Latella M, et al.
Nucleic Acids Res
. 2024 May;
52(W1):W29-W38.
PMID: 38795068
Gene therapy of dominantly inherited genetic diseases requires either the selective disruption of the mutant allele or the editing of the specific mutation. The CRISPR-Cas system holds great potential for...
8.
Polito M, Marini G, Palamenghi M, Enzo E
Int J Mol Sci
. 2023 May;
24(10).
PMID: 37239891
The epidermis is one of the largest tissues in the human body, serving as a protective barrier. The basal layer of the epidermis, which consists of epithelial stem cells and...
9.
De Rosa L, Enzo E, Palamenghi M, Sercia L, De Luca M
Cold Spring Harb Perspect Biol
. 2022 Sep;
15(4).
PMID: 36167646
Epidermolysis bullosa (EB) is a devastating genetic skin disease typified by a plethora of different phenotypes and ranking from severe, early lethal, to mild localized forms. Although there is no...
10.
Enzo E, Cattaneo C, Consiglio F, Polito M, Bondanza S, De Luca M
Methods Cell Biol
. 2022 Jul;
170:101-116.
PMID: 35811094
Regenerative medicine has its roots in harnessing stem cells for permanent restoration of damaged or diseased tissues. The first procedure for the transplantation of epidermal cultures in massive full-thickness burns...