Sergei Kusmartsev
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Explore the profile of Sergei Kusmartsev including associated specialties, affiliations and a list of published articles.
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40
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3873
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Recent Articles
11.
Crispen P, Kusmartsev S
Cancer Immunol Immunother
. 2019 Dec;
69(1):3-14.
PMID: 31811337
With the introduction of multiple new agents, the role of immunotherapy is rapidly expanding across all malignancies. Bladder cancer is known to be immunogenic and is responsive to immunotherapy including...
12.
Dominguez-Gutierrez P, Kusmartsev S, Canales B, Khan S
Front Immunol
. 2018 Sep;
9:1863.
PMID: 30186283
Purpose: A number of hyperoxaluric states have been associated with calcium oxalate (CaOx) deposits in the kidneys. In animal models of stone disease, these crystals interact with circulating monocytes that...
13.
Prima V, Kaliberova L, Kaliberov S, Curiel D, Kusmartsev S
Proc Natl Acad Sci U S A
. 2017 Jan;
114(5):1117-1122.
PMID: 28096371
In recent years, it has been established that programmed cell death protein ligand 1 (PD-L1)-mediated inhibition of activated PD-1 T lymphocytes plays a major role in tumor escape from immune...
14.
Kusmartsev S, Dominguez-Gutierrez P, Canales B, Bird V, Vieweg J, Khan S
J Urol
. 2015 Dec;
195(4 Pt 1):1143-51.
PMID: 26626217
Purpose: In murine and human hyperoxaluric conditions macrophages can be seen surrounding renal calcium oxalate crystal deposits. We hypothesized that macrophages have a role in degrading and destroying these deposits....
15.
Eruslanov E, Stoffs T, Kim W, Daurkin I, Gilbert S, Su L, et al.
Clin Cancer Res
. 2013 Feb;
19(7):1670-80.
PMID: 23363815
Purpose: Chemokines are involved in cancer-related inflammation and malignant progression. In this study, we evaluated expression of CCR8 and its natural cognate ligand CCL1 in patients with urothelial carcinomas of...
16.
Kusmartsev S
Oncoimmunology
. 2012 Jun;
1(2):249-251.
PMID: 22720260
Macrophage infiltration is a hallmark in the majority of solid tumors. Our studies demonstrated that macrophages that infiltrate human renal cells carcinoma (RCC) display markedly enhanced expression and activity of...
17.
Daurkin I, Eruslanov E, Stoffs T, Perrin G, Algood C, Gilbert S, et al.
Cancer Res
. 2011 Sep;
71(20):6400-9.
PMID: 21900394
Renal cell carcinoma (RCC), the most common human kidney cancer, is frequently infiltrated with tumor-associated macrophages (TAM) that can promote malignant progression. Here, we show that TAMs isolated from human...
18.
Eruslanov E, Neuberger M, Daurkin I, Perrin G, Algood C, Dahm P, et al.
Int J Cancer
. 2011 Apr;
130(5):1109-19.
PMID: 21480223
Both cancer-related inflammation and tumor-induced immune suppression are associated with expansion of myeloid cell subsets including myeloid-derived suppressor cells. However, little known regarding characteristics of myeloid cells in patients with...
19.
Eruslanov E, Daurkin I, Vieweg J, Daaka Y, Kusmartsev S
Int Immunopharmacol
. 2011 Feb;
11(7):848-55.
PMID: 21315786
Bladder cancer is associated with enhanced inflammation and characterized by deregulated prostanoid metabolism. Here we examined prostaglandin E₂ (PGE₂) metabolism and myeloid cell subsets that infiltrate tumor tissue using two...
20.
Eruslanov E, Daurkin I, Ortiz J, Vieweg J, Kusmartsev S
J Leukoc Biol
. 2010 Jul;
88(5):839-48.
PMID: 20587738
Recent studies suggest that tumor-infiltrated myeloid cells frequently up-regulate COX-2 expression and have enhanced PGE₂ metabolism. This may affect the maturation and immune function of tumor-infiltrated antigen-presenting cells. In vitro...