Seref Gul
Overview
Explore the profile of Seref Gul including associated specialties, affiliations and a list of published articles.
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29
Citations
251
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Recent Articles
1.
Akyel Y, Seyhan N, Gul S, Celik M, Taskin A, Selby C, et al.
Arch Toxicol
. 2025 Feb;
PMID: 39903276
Circadian rhythms, the 24-h oscillations of biological activities guided by the molecular clock, play a pivotal role in regulating various physiological processes in organisms. The intricate relationship between the loss...
2.
Simsek H, Gul S
J Biomol Struct Dyn
. 2024 Nov;
:1-21.
PMID: 39533921
Lassa fever, caused by the zoonotic Lassa virus (LASV), poses a significant health threat in Africa, leading to thousands of infections and deaths annually and has the potential to spread...
3.
Taskin A, Kocabay A, Gul S, Sahin G, Karahuseyinoglu S, Kavakli I, et al.
Zygote
. 2024 Oct;
32(5):348-353.
PMID: 39431373
Boric acid (BA) is an important mineral for plants, animals and humans that assists metabolic function and has both positive and negative effects on biological systems. The present study aimed...
4.
Parlak G, Baris I, Gul S, Kavakli I
J Biol Chem
. 2023 Nov;
299(12):105451.
PMID: 37951306
Cryptochromes (CRYs) are essential components of the circadian clock, playing a pivotal role as transcriptional repressors. Despite their significance, the precise mechanisms underlying CRYs' involvement in the circadian clock remain...
5.
Surme S, Ergun C, Gul S, Akyel Y, Gul Z, Ozcan O, et al.
Biochem Pharmacol
. 2023 Oct;
218:115896.
PMID: 37898388
Cryptochromes (CRYs), transcriptional repressors of the circadian clock in mammals, inhibit cAMP production when glucagon activates G-protein coupled receptors. Therefore, molecules that modulate CRYs have the potential to regulate gluconeogenesis....
6.
Ozcan O, Gul S, Kavakli I
J Biomol Struct Dyn
. 2023 Sep;
42(19):10417-10428.
PMID: 37705288
Cryptochromes (CRYs) are essential components of the molecular clock that generates circadian rhythm. They inhibit BMAL1/CLOCK-driven transcription at the molecular level. There are two CRYs that have differential functions in...
7.
Akyel Y, Ozturk Civelek D, Seyhan N, Gul S, Gazioglu I, Pala Kara Z, et al.
J Biol Rhythms
. 2023 Feb;
38(2):171-184.
PMID: 36762608
The circadian timing system controls absorption, distribution, metabolism, and elimination processes of drug pharmacokinetics over a 24-h period. Exposure of target tissues to the active form of the drug and...
8.
Gul S, Akyel Y, Gul Z, Isin S, Ozcan O, Korkmaz T, et al.
Nat Commun
. 2022 Nov;
13(1):6742.
PMID: 36347873
Cryptochromes are negative transcriptional regulators of the circadian clock in mammals. It is not clear how reducing the level of endogenous CRY1 in mammals will affect circadian rhythm and the...
9.
Parlak G, Camur B, Gul S, Ozcan O, Baris I, Kavakli I
J Biol Chem
. 2022 Aug;
298(9):102334.
PMID: 35933018
Human clock-gene variations contribute to the phenotypic differences observed in various behavioral and physiological processes, such as diurnal preference, sleep, metabolism, mood regulation, addiction, and fertility. However, little is known...
10.
Duman N, Tuncel G, Bisgin A, Bozdogan S, Sag S, Gul S, et al.
J Med Virol
. 2022 Jul;
94(11):5225-5243.
PMID: 35811452
Heterogeneity in symptoms associated with COVID-19 in infected patients remains unclear. ACE2 and TMPRSS2 gene variants are considered possible risk factors for COVID-19. In this study, a retrospective comparative genome...