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Sepideh Aboutorabian

Explore the profile of Sepideh Aboutorabian including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Hakimi J, Aboutorabian S, To F, Ausar S, Rahman N, Brookes R
Methods Mol Biol . 2016 Oct; 1494:295-304. PMID: 27718203
Monitoring the immunological functionality of vaccine formulations is critical for vaccine development. While the traditional approach using established animal models has been relatively effective, the use of animals is costly...
2.
Hasija M, Aboutorabian S, Rahman N, Ausar S
Methods Mol Biol . 2016 Apr; 1403:853-66. PMID: 27076171
During the early stages of vaccine development, forced degradation studies are conducted to provide information about the degradation properties of vaccine formulations. In addition to supporting the development of analytical...
3.
Aboutorabian S, Hakimi J, Boudet F, Montano S, Dookie A, Roque C, et al.
Hum Vaccin Immunother . 2015 May; 11(6):1449-55. PMID: 25997147
A tuberculosis (TB) vaccine consisting of a recombinant fusion protein (H4) and a novel TLR9 adjuvant (IC31) is in clinical development. To better understand the H4-IC31 ratio, we measured the...
4.
Brookes R, Hakimi J, Ha Y, Aboutorabian S, Ausar S, Hasija M, et al.
Hum Vaccin Immunother . 2014 Jan; 10(4):1129-35. PMID: 24401565
Understanding the relevant biological activity of any pharmaceutical formulation destined for human use is crucial. For vaccine-based formulations, activity must reflect the expected immune response, while for non-vaccine therapeutic agents,...