Jalil Hakimi
Overview
Explore the profile of Jalil Hakimi including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
194
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0
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Recent Articles
1.
Hakimi J, Azizi A, Ausar S, Todryk S, Rahman N, Brookes R
Hum Vaccin Immunother
. 2017 Jun;
13(9):2130-2134.
PMID: 28605295
The restimulation of an immune memory response by in vitro culture of blood cells with a specific antigen has been used as a way to gauge immunity to vaccines for...
2.
Hakimi J, Aboutorabian S, To F, Ausar S, Rahman N, Brookes R
Methods Mol Biol
. 2016 Oct;
1494:295-304.
PMID: 27718203
Monitoring the immunological functionality of vaccine formulations is critical for vaccine development. While the traditional approach using established animal models has been relatively effective, the use of animals is costly...
3.
Aboutorabian S, Hakimi J, Boudet F, Montano S, Dookie A, Roque C, et al.
Hum Vaccin Immunother
. 2015 May;
11(6):1449-55.
PMID: 25997147
A tuberculosis (TB) vaccine consisting of a recombinant fusion protein (H4) and a novel TLR9 adjuvant (IC31) is in clinical development. To better understand the H4-IC31 ratio, we measured the...
4.
Brookes R, Hakimi J, Ha Y, Aboutorabian S, Ausar S, Hasija M, et al.
Hum Vaccin Immunother
. 2014 Jan;
10(4):1129-35.
PMID: 24401565
Understanding the relevant biological activity of any pharmaceutical formulation destined for human use is crucial. For vaccine-based formulations, activity must reflect the expected immune response, while for non-vaccine therapeutic agents,...
5.
He L, Hakimi J, Salha D, Miron I, Dunn P, Radvanyi L
J Immunol Methods
. 2005 Aug;
304(1-2):43-59.
PMID: 16076473
We describe a highly sensitive flow cytometry-based CTL assay using the cleavage of caspase 3 in target cells as a readout. The assay involved labeling of cells with a cell...
6.
Radvanyi L, Singh-Sandhu D, Gallichan S, Lovitt C, Pedyczak A, Mallo G, et al.
Proc Natl Acad Sci U S A
. 2005 Jul;
102(31):11005-10.
PMID: 16043716
A comprehensive differential gene expression screen on a panel of 54 breast tumors and >200 normal tissue samples using DNA microarrays revealed 15 genes specifically overexpressed in breast cancer. One...