Seishiro Hirano
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Explore the profile of Seishiro Hirano including associated specialties, affiliations and a list of published articles.
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111
Citations
1620
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Recent Articles
1.
Udagawa O, Kato-Udagawa A, Hirano S
Int J Mol Sci
. 2024 Aug;
25(16).
PMID: 39201340
Promyelocytic leukemia (PML) nuclear bodies (PML-NBs) are core-shell-type membrane-less organelles typically found in the nucleus of mammalian somatic cells but are absent in mouse oocytes. Here, we deliberately induced the...
2.
Kanno S, Hirano S, Monma-Otaki J, Kato H, Fukuta M, Nakamura Y, et al.
J Toxicol Sci
. 2023 Feb;
48(2):75-86.
PMID: 36725023
Quaternary ammonium compounds, including benzalkonium chloride (BAC) and cetylpyridinium chloride (CPC), are widely used as disinfectants. Increased use of inhalable products containing BAC or CPC has raised concerns for lung...
3.
Kyi-Tha-Thu C, Fujitani Y, Hirano S, Win-Shwe T
Int J Mol Sci
. 2023 Jan;
24(1).
PMID: 36614034
Recent epidemiological studies have reported significantly increasing hospital admission rates for mental disorders such as anxiety and depression, not only in adults but also in children and adolescents, indicating more...
4.
Hirano S, Udagawa O
PLoS One
. 2022 May;
17(5):e0268835.
PMID: 35594310
Promyelocytic leukemia (PML) proteins are involved in the pathogenesis of acute promyelocytic leukemia (APL). Trivalent arsenic (As3+) is known to cure APL by binding to cysteine residues of PML and...
5.
Udagawa O, Kato-Udagawa A, Hirano S
Biol Open
. 2022 May;
11(6).
PMID: 35579421
Promyelocytic leukemia (PML) nuclear bodies (PML-NBs), a class of membrane-less cellular organelles, participate in various biological activities. PML-NBs are known as the core-shell-type nuclear body, harboring 'client' proteins in their...
6.
Hirano S, Udagawa O
Arch Toxicol
. 2022 Jan;
96(2):545-558.
PMID: 35001170
The functional roles of protein modification by small ubiquitin-like modifier (SUMO) proteins are not well understood compared to ubiquitination. Promyelocytic leukemia (PML) proteins are good substrates for SUMOylation, and PML-nuclear...
7.
Win-Shwe T, Kyi-Tha-Thu C, Fujitani Y, Tsukahara S, Hirano S
Int J Mol Sci
. 2021 Jan;
22(2).
PMID: 33430368
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impaired social communication, poor social interactions, and repetitive behaviors. We aimed to examine autism-like behaviors and related gene expressions in...
8.
Kanno S, Hirano S, Sakamoto T, Furuyama A, Takase H, Kato H, et al.
Sci Rep
. 2020 Dec;
10(1):21795.
PMID: 33311558
Macrophage receptor with collagenous structure (MARCO) is a scavenger receptor class-A protein that is expressed on the cell surface of macrophages. MARCO mediates binding and ingestion of unopsonized environmental particles,...
9.
Hirano S
Arch Toxicol
. 2020 May;
94(8):2587-2601.
PMID: 32435915
Arsenic is a well-known environmental carcinogen and chronic exposure to arsenic through drinking water has been reported to cause skin, bladder and lung cancers, with arsenic metabolites being implicated in...
10.
Hirano S, Kanno S
Toxicol In Vitro
. 2020 Mar;
65:104816.
PMID: 32126253
Autophagy molecules such as microtubule-associated protein light chain 3 (LC3) and p62/SQSTM1 have been used as biomarkers of protective or conversely adverse effects of exposure to toxicants. In the present...