Sebastien Moniot
Overview
Explore the profile of Sebastien Moniot including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
840
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0
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Recent Articles
1.
Wurster V, Fechner P, Proll G, Pamies-Cuberos R, Frech M, Baumgartner J, et al.
Anal Bioanal Chem
. 2025 Feb;
PMID: 39930259
Kinases are involved in numerous cellular processes but possibly also in tumor progression. Several kinase inhibitors are approved as drugs and there is an intense search for new inhibitors in...
2.
Mariottini D, Bracaglia S, Barbero L, Fuchs S, Saal C, Moniot S, et al.
ACS Sens
. 2023 Oct;
8(11):4014-4019.
PMID: 37856082
We report here the development of two different sensing strategies based on the use of antigen-conjugated nucleic acid strands for the detection of a bispecific antibody against the tumor-related proteins...
3.
Linder J, Hupfeld E, Weyand M, Steegborn C, Moniot S
J Struct Biol
. 2020 May;
211(2):107534.
PMID: 32454240
In many organisms, the ubiquitous second messenger cAMP is formed by at least one member of the adenylyl cyclase (AC) Class III. These ACs feature a conserved dimeric catalytic core...
4.
Weber A, Kaiser J, Ziegler T, Pilsl S, Renzl C, Sixt L, et al.
Nat Chem Biol
. 2019 Aug;
15(11):1085-1092.
PMID: 31451761
Sensory photoreceptor proteins underpin light-dependent adaptations in nature and enable the optogenetic control of organismal behavior and physiology. We identified the bacterial light-oxygen-voltage (LOV) photoreceptor PAL that sequence-specifically binds short...
5.
Pinto A, El Ali Z, Moniot S, Tamborini L, Steegborn C, Foresti R, et al.
ChemistryOpen
. 2018 Nov;
7(11):858-864.
PMID: 30397576
Natural and synthetic electrophilic compounds have been shown to activate the antioxidant protective Nrf2 (nuclear factor erythroid 2-related factor 2)/heme oxygenase-1 (HO-1) axis in cells and tissues. Here, we tested...
6.
Quinti L, Naidu S, Trager U, Chen X, Kegel-Gleason K, Lleres D, et al.
Proc Natl Acad Sci U S A
. 2017 May;
114(23):E4676-E4685.
PMID: 28533375
The activity of the transcription factor nuclear factor-erythroid 2 p45-derived factor 2 (NRF2) is orchestrated and amplified through enhanced transcription of antioxidant and antiinflammatory target genes. The present study has...
7.
de Oliveira R, Miranda H, Francelle L, Pinho R, Szego E, Martinho R, et al.
PLoS Biol
. 2017 Apr;
15(4):e1002601.
PMID: 28379951
[This corrects the article DOI: 10.1371/journal.pbio.2000374.].
8.
Li J, Bonkowski M, Moniot S, Zhang D, Hubbard B, Ling A, et al.
Science
. 2017 Mar;
355(6331):1312-1317.
PMID: 28336669
DNA repair is essential for life, yet its efficiency declines with age for reasons that are unclear. Numerous proteins possess Nudix homology domains (NHDs) that have no known function. We...
9.
de Oliveira R, Miranda H, Francelle L, Pinho R, Szego E, Martinho R, et al.
PLoS Biol
. 2017 Mar;
15(3):e2000374.
PMID: 28257421
Sirtuin genes have been associated with aging and are known to affect multiple cellular pathways. Sirtuin 2 was previously shown to modulate proteotoxicity associated with age-associated neurodegenerative disorders such as...
10.
Moniot S, Forgione M, Lucidi A, Hailu G, Nebbioso A, Carafa V, et al.
J Med Chem
. 2017 Feb;
60(6):2344-2360.
PMID: 28240897
Sirt2 is a target for the treatment of neurological, metabolic, and age-related diseases including cancer. Here we report a series of Sirt2 inhibitors based on the 1,2,4-oxadiazole scaffold. These compounds...