Sebastien Besseau
Overview
Explore the profile of Sebastien Besseau including associated specialties, affiliations and a list of published articles.
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Articles
68
Citations
1449
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Recent Articles
1.
Meteignier L, Szwarc S, Barunava P, Durand M, Zamar D, Birer Williams C, et al.
Plant Physiol Biochem
. 2024 Dec;
219:109363.
PMID: 39657422
Monoterpene indole alkaloids (MIAs) are valuable metabolites produced in numerous medicinal plants from the Apocynaceae family such as Alstonia scholaris, which synthesizes strictamine, a MIA displaying neuropharmacological properties of a...
2.
Lezin E, Durand M, Birer Williams C, Lopez Vazquez A, Perrot T, Gautron N, et al.
Plant J
. 2024 Oct;
120(5):1880-1900.
PMID: 39427334
Plant-specialized metabolism represents an inexhaustible source of active molecules, some of which have been used in human health for decades. Among these, monoterpene indole alkaloids (MIAs) include a wide range...
3.
Roumani M, Besseau S, Hehn A, Larbat R
Phytochemistry
. 2024 Sep;
229:114271.
PMID: 39260586
Phenolamides are specialized metabolites widely distributed in the plant kingdom. Their structure is composed by the association of hydroxycinnamic acid derivatives to mono-/poly-amine through an amination catalyzed by N-hydroxycinnamoyltransferases enzymes....
4.
Durand M, Besseau S, Papon N, Courdavault V
Curr Opin Biotechnol
. 2024 May;
87:103135.
PMID: 38728826
Plant bioactives hold immense potential in the medicine and food industry. The recent advancements in omics applied in deciphering specialized metabolic pathways underscore the importance of high-quality genome releases and...
5.
Bradley S, Hansson F, Lehka B, Rago D, Pinho P, Peng H, et al.
ACS Synth Biol
. 2024 Apr;
13(5):1498-1512.
PMID: 38635307
Monoterpene indole alkaloids (MIAs) make up a highly bioactive class of metabolites produced by a range of tropical and subtropical plants. The corynanthe-type MIAs are a stereochemically complex subclass with...
6.
Cuello C, Jansen H, Abdallah C, Zamar Mbadinga D, Birer Williams C, Durand M, et al.
Heliyon
. 2024 Mar;
10(6):e28078.
PMID: 38533072
Specialized metabolites possess diverse interesting biological activities and some cardenolides- and monoterpene indole alkaloids- (MIAs) derived pharmaceuticals are currently used to treat human diseases such as cancers or hypertension. While...
7.
Perrot T, Marc J, Lezin E, Papon N, Besseau S, Courdavault V
Curr Opin Biotechnol
. 2024 Mar;
87:103098.
PMID: 38452572
Natural products represent an inestimable source of valuable compounds for human health. Notably, those produced by plants remain challenging to access due to their low production. Potential shortages of plant-derived...
8.
Lezin E, Carqueijeiro I, Cuello C, Durand M, Jansen H, Verges V, et al.
Plant Commun
. 2023 Dec;
5(4):100784.
PMID: 38155576
No abstract available.
9.
Stander E, Lehka B, Carqueijeiro I, Cuello C, Hansson F, Jansen H, et al.
Commun Biol
. 2023 Nov;
6(1):1197.
PMID: 38001233
Monoterpene indole alkaloids (MIAs) are a structurally diverse family of specialized metabolites mainly produced in Gentianales to cope with environmental challenges. Due to their pharmacological properties, the biosynthetic modalities of...
10.
Bradley S, Lehka B, Hansson F, Adhikari K, Rago D, Rubaszka P, et al.
Nat Chem Biol
. 2023 Nov;
19(12):1551-1560.
PMID: 37932529
Monoterpenoid indole alkaloids (MIAs) represent a large class of plant natural products with marketed pharmaceutical activities against a wide range of indications, including cancer, malaria and hypertension. Halogenated MIAs have...