Sebastian Tiesmeyer
Overview
Explore the profile of Sebastian Tiesmeyer including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
137
Followers
0
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Recent Articles
1.
Muller-Botticher N, Tiesmeyer S, Eils R, Ishaque N
Small Methods
. 2024 Nov;
:e2401123.
PMID: 39533496
Spatially resolved transcriptomics (SRT) has become the method of choice for characterising the complexity of biomedical tissue samples. Until recently, scientists were restricted to SRT methods that can profile a...
2.
Nonn O, Debnath O, Valdes D, Sallinger K, Secener A, Fischer C, et al.
Hypertension
. 2024 Oct;
PMID: 39440423
Background: Preeclampsia is a severe hypertensive disorder in pregnancy that causes preterm delivery, maternal and fetal morbidity, mortality, and life-long sequelae. Understanding the pathogenesis of preeclampsia is a critical first...
3.
Tiesmeyer S, Sahay S, Muller-Botticher N, Eils R, Mackowiak S, Ishaque N
Front Genet
. 2022 Mar;
13:785877.
PMID: 35295943
The combination of a cell's transcriptional profile and location defines its function in a spatial context. Spatially resolved transcriptomics (SRT) has emerged as the assay of choice for characterizing cells...
4.
Park J, Choi W, Tiesmeyer S, Long B, Borm L, Garren E, et al.
Nat Commun
. 2021 Jun;
12(1):4103.
PMID: 34183662
No abstract available.
5.
Park J, Choi W, Tiesmeyer S, Long B, Borm L, Garren E, et al.
Nat Commun
. 2021 Jun;
12(1):3545.
PMID: 34112806
Multiplexed fluorescence in situ hybridization techniques have enabled cell-type identification, linking transcriptional heterogeneity with spatial heterogeneity of cells. However, inaccurate cell segmentation reduces the efficacy of cell-type identification and tissue...
6.
Tosti L, Hang Y, Debnath O, Tiesmeyer S, Trefzer T, Steiger K, et al.
Gastroenterology
. 2020 Nov;
160(4):1330-1344.e11.
PMID: 33212097
Background & Aims: Molecular evidence of cellular heterogeneity in the human exocrine pancreas has not been yet established because of the local concentration and cascade of hydrolytic enzymes that can...