Thuc Nghi Nguyen
Overview
Explore the profile of Thuc Nghi Nguyen including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
7026
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Recent Articles
1.
Yao Z, van Velthoven C, Kunst M, Zhang M, McMillen D, Lee C, et al.
Nature
. 2023 Dec;
624(7991):317-332.
PMID: 38092916
The mammalian brain consists of millions to billions of cells that are organized into many cell types with specific spatial distribution patterns and structural and functional properties. Here we report...
2.
Yao Z, van Velthoven C, Kunst M, Zhang M, McMillen D, Lee C, et al.
bioRxiv
. 2023 Apr;
PMID: 37034735
The mammalian brain is composed of millions to billions of cells that are organized into numerous cell types with specific spatial distribution patterns and structural and functional properties. An essential...
3.
Condylis C, Ghanbari A, Manjrekar N, Bistrong K, Yao S, Yao Z, et al.
Science
. 2022 Jan;
375(6576):eabl5981.
PMID: 34990233
Although single-cell transcriptomics of the neocortex has uncovered more than 300 putative cell types, whether this molecular classification predicts distinct functional roles is unclear. We combined two-photon calcium imaging with...
4.
Peng H, Xie P, Liu L, Kuang X, Wang Y, Qu L, et al.
Nature
. 2021 Oct;
598(7879):174-181.
PMID: 34616072
Dendritic and axonal morphology reflects the input and output of neurons and is a defining feature of neuronal types, yet our knowledge of its diversity remains limited. Here, to systematically...
5.
Yao Z, Liu H, Xie F, Fischer S, Adkins R, Aldridge A, et al.
Nature
. 2021 Oct;
598(7879):103-110.
PMID: 34616066
Single-cell transcriptomics can provide quantitative molecular signatures for large, unbiased samples of the diverse cell types in the brain. With the proliferation of multi-omics datasets, a major challenge is to...
6.
Bakken T, van Velthoven C, Menon V, Hodge R, Yao Z, Nguyen T, et al.
Elife
. 2021 Sep;
10.
PMID: 34473054
Abundant evidence supports the presence of at least three distinct types of thalamocortical (TC) neurons in the primate dorsal lateral geniculate nucleus (dLGN) of the thalamus, the brain region that...
7.
Park J, Choi W, Tiesmeyer S, Long B, Borm L, Garren E, et al.
Nat Commun
. 2021 Jun;
12(1):4103.
PMID: 34183662
No abstract available.
8.
Park J, Choi W, Tiesmeyer S, Long B, Borm L, Garren E, et al.
Nat Commun
. 2021 Jun;
12(1):3545.
PMID: 34112806
Multiplexed fluorescence in situ hybridization techniques have enabled cell-type identification, linking transcriptional heterogeneity with spatial heterogeneity of cells. However, inaccurate cell segmentation reduces the efficacy of cell-type identification and tissue...
9.
Yao Z, van Velthoven C, Nguyen T, Goldy J, Sedeno-Cortes A, Baftizadeh F, et al.
Cell
. 2021 May;
184(12):3222-3241.e26.
PMID: 34004146
The isocortex and hippocampal formation (HPF) in the mammalian brain play critical roles in perception, cognition, emotion, and learning. We profiled ∼1.3 million cells covering the entire adult mouse isocortex...
10.
Graybuck L, Daigle T, Sedeno-Cortes A, Walker M, Kalmbach B, Lenz G, et al.
Neuron
. 2021 Mar;
109(9):1449-1464.e13.
PMID: 33789083
Rapid cell type identification by new genomic single-cell analysis methods has not been met with efficient experimental access to these cell types. To facilitate access to specific neural populations in...