Sebastian T Balbach
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Explore the profile of Sebastian T Balbach including associated specialties, affiliations and a list of published articles.
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10
Citations
77
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Recent Articles
1.
Fischer A, Albert T, Moreno N, Interlandi M, Mormann J, Glaser S, et al.
Nat Commun
. 2024 Oct;
15(1):8571.
PMID: 39362842
Peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS) is a heterogeneous group of malignancies with poor outcome. Here, we identify a subgroup, PTCL-NOS, which is characterized by the lack of the...
2.
Fuest S, Post C, Balbach S, Jabar S, Neumann I, Schimmelpfennig S, et al.
Cancers (Basel)
. 2022 Oct;
14(19).
PMID: 36230742
Ewing sarcoma (EwS) is a rare and highly malignant bone tumor occurring mainly in childhood and adolescence. Physiologically, the bone is a central hub for Ca homeostasis, which is severely...
3.
Balbach S, Orkin S
Cancer Discov
. 2016 Jul;
6(7):700-2.
PMID: 27371576
Histone H3 lysine 36 dimethylation (H3K36me2), a modification associated with transcriptional activation, is required for mixed-lineage leukemia-dependent transcription and leukemic transformation. In this issue of Cancer Discovery, Zhu and colleagues...
4.
Balbach S, Boiani M
Methods Mol Biol
. 2014 Oct;
1222:149-59.
PMID: 25287344
Nuclear transfer (NT) into mouse oocytes yields a transcriptionally and functionally heterogeneous population of cloned embryos. Most studies of NT embryos consider only embryos at predefined key stages (e.g., morula...
5.
Pfeiffer M, Esteves T, Balbach S, Arauzo-Bravo M, Stehling M, Jauch A, et al.
Stem Cells
. 2013 Aug;
31(11):2343-53.
PMID: 23922292
The conversion of the nuclear program of a somatic cell from a differentiated to an undifferentiated state can be accomplished by transplanting its nucleus to an enucleated oocyte (somatic cell...
6.
Esteves T, Psathaki O, Pfeiffer M, Balbach S, Zeuschner D, Shitara H, et al.
PLoS One
. 2012 Jun;
7(6):e36850.
PMID: 22693623
While reprogramming a foreign nucleus after somatic cell nuclear transfer (SCNT), the enucleated oocyte (ooplasm) must signal that biomass and cellular requirements changed compared to the nucleus donor cell. Using...
7.
Pfeiffer M, Siatkowski M, Paudel Y, Balbach S, Baeumer N, Crosetto N, et al.
J Proteome Res
. 2011 Feb;
10(5):2140-53.
PMID: 21344949
The oocyte is the only cell of the body that can reprogram transplanted somatic nuclei and sets the gold standard for all reprogramming methods. Therefore, an in-depth characterization of its...
8.
Pfeiffer M, Balbach S, Esteves T, Crosetto N, Boiani M
Int J Dev Biol
. 2010 Dec;
54(11-12):1649-57.
PMID: 21136379
Cloned mouse embryo development to blastocyst stage correlates positively with the expression level of Oct4 (Pou5f1) at the morula stage, as reported previously by our laboratory. However, whether this correlation...
9.
Cavaleri F, Balbach S, Gentile L, Jauch A, Bohm-Steuer B, Han Y, et al.
Mech Dev
. 2007 Dec;
125(1-2):153-66.
PMID: 18054470
An important question in oocyte-mediated nuclear reprogramming is whether gene expression of the donor nucleus changes randomly or follows a pattern. Since cloned embryos are very heterogeneous and arrest frequently...
10.
Balbach S, Jauch A, Bohm-Steuer B, Cavaleri F, Han Y, Boiani M
Dev Biol
. 2007 Jul;
308(2):309-21.
PMID: 17610862
The mechanisms that have evolved to maintain genome stability during cell cycle progression are challenged when a somatic cell nucleus is placed in a meiotic environment such as the ooplasm....