Sebastian E J Ludwig
Overview
Explore the profile of Sebastian E J Ludwig including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
25
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Recent Articles
1.
Zhang Z, Kumar V, Dybkov O, Will C, Zhong J, Ludwig S, et al.
Nature
. 2024 May;
630(8018):1012-1019.
PMID: 38778104
Early spliceosome assembly can occur through an intron-defined pathway, whereby U1 and U2 small nuclear ribonucleoprotein particles (snRNPs) assemble across the intron. Alternatively, it can occur through an exon-defined pathway,...
2.
Georgiou M, Yang C, Atkinson R, Pan K, Buskin A, Moya Molina M, et al.
Clin Transl Med
. 2022 Mar;
12(3):e759.
PMID: 35297555
Introduction: Mutations in pre-mRNA processing factor 31 (PRPF31), a core protein of the spliceosomal tri-snRNP complex, cause autosomal-dominant retinitis pigmentosa (adRP). It has remained an enigma why mutations in ubiquitously...
3.
Yildirim A, Mozaffari-Jovin S, Wallisch A, Schafer J, Ludwig S, Urlaub H, et al.
Nucleic Acids Res
. 2021 May;
49(10):5845-5866.
PMID: 34023904
Splicing is catalyzed by the spliceosome, a compositionally dynamic complex assembled stepwise on pre-mRNA. We reveal links between splicing machinery components and the intrinsically disordered ciliopathy protein SANS. Pathogenic mutations...