Sean Wasserman
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Explore the profile of Sean Wasserman including associated specialties, affiliations and a list of published articles.
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93
Citations
1215
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Recent Articles
1.
Youngquist B, Mnguni A, Pungan D, Lai R, Dai G, Ng C, et al.
J Clin Invest
. 2025 Mar;
PMID: 40029713
Background: Pneumocystis jirovecii pneumonia (PCP) is a leading cause of fungal pneumonia, but its diagnosis primarily relies on invasive bronchoalveolar lavage (BAL) specimens that are difficult to obtain. Oropharyngeal swabs...
2.
Mdlenyani L, Mohamed Z, Stadler J, Mtwa N, Meintjes G, Warren R, et al.
medRxiv
. 2025 Feb;
PMID: 39974042
Background: Rising prevalence of bedaquiline resistance undermines benefits from this life-saving drug for rifampicin-resistant tuberculosis (RR-TB). Despite increasing awareness, patient-level outcomes for bedaquiline-resistant TB have not been well-characterised and case...
3.
Guglielmetti L, Khan U, Velasquez G, Gouillou M, Abubakirov A, Baudin E, et al.
N Engl J Med
. 2025 Jan;
392(5):468-482.
PMID: 39879593
Background: For decades, poor treatment options and low-quality evidence plagued care for patients with rifampin-resistant tuberculosis. The advent of new drugs to treat tuberculosis and enhanced funding now permit randomized,...
4.
Maputla S, Joubert A, Castel S, Merwe M, Zangenberg E, Wasserman S, et al.
J Pharm Biomed Anal
. 2024 Dec;
255():116613.
PMID: 39653626
For the effective treatment of tuberculosis with first-line anti-tubercular drugs, drug concentrations need to be measured at the site of infection to determine drug exposure. To enable the measurement of...
5.
Wills N, Tavares J, Said-Hartley Q, Wasserman S
South Afr J HIV Med
. 2024 Dec;
25(1):1636.
PMID: 39649953
Background: Definition of chest X-ray (CXR) features associated with laboratory-confirmed pneumocystis pneumonia (PCP) among HIV-positive adults is needed to improve diagnosis in high-burden settings. Objectives: Our primary objective was to...
6.
Wasserman S, Donovan J, Kestelyn E, Watson J, Aarnoutse R, Barnacle J, et al.
Lancet Infect Dis
. 2024 Sep;
25(1):e47-e58.
PMID: 39342951
Tuberculous meningitis causes death or disability in approximately 50% of affected individuals and kills approximately 78 200 adults every year. Antimicrobial treatment is based on regimens used for pulmonary tuberculosis,...
7.
Wasserman S, Antilus-Sainte R, Abdelgawad N, Odjourian N, Cristaldo M, Dougher M, et al.
Antimicrob Agents Chemother
. 2024 Jul;
68(8):e0078324.
PMID: 39028192
Tuberculous meningitis (TBM) has a high mortality, possibly due to suboptimal therapy. Drug exposure data of antituberculosis agents in the central nervous system (CNS) are required to develop more effective...
8.
Namale P, Boloko L, Vermeulen M, Haigh K, Bagula F, Maseko A, et al.
Trials
. 2024 May;
25(1):311.
PMID: 38720383
Background: HIV-associated tuberculosis (TB) contributes disproportionately to global tuberculosis mortality. Patients hospitalised at the time of the diagnosis of HIV-associated disseminated TB are typically severely ill and have a high...
9.
Wills N, Adriaanse M, Erasmus S, Wasserman S
Open Forum Infect Dis
. 2024 Apr;
11(4):ofae146.
PMID: 38628951
Background: The performance of chest x-ray (CXR) features for pneumonia (PCP) diagnosis has been evaluated in small studies. We conducted a systematic review and meta-analysis to describe CXR changes in...
10.
Hermans L, Booysen P, Boloko L, Adriaanse M, de Wet T, Lifson A, et al.
S Afr J Infect Dis
. 2024 Jan;
38(1):550.
PMID: 38223432
Background: The emergence of genetic variants of SARS-CoV-2 was associated with changing epidemiological characteristics throughout coronavirus disease 2019 (COVID-19) pandemic in population-based studies. Individual-level data on the clinical characteristics of...