Sean P Troth
Overview
Explore the profile of Sean P Troth including associated specialties, affiliations and a list of published articles.
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Articles
24
Citations
317
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0
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Recent Articles
1.
Escobar P, Sobol Z, Miller R, Ferry-Martin S, Stermer A, Jacob B, et al.
Toxicol Sci
. 2024 Dec;
204(1):118-119.
PMID: 39693107
No abstract available.
2.
Escobar P, Sobol Z, Miller R, Ferry-Martin S, Stermer A, Jacob B, et al.
Toxicol Sci
. 2024 Sep;
202(2):278-290.
PMID: 39302733
Molnupiravir is registered or authorized in several countries as a 5-d oral coronavirus disease 2019 treatment for adults. Molnupiravir is a prodrug of the antiviral ribonucleoside β-D-N4-hydroxycytidine (NHC) that distributes...
3.
Gu Y, Paul E, Vlasakova K, Troth S, Sistare F, Ramaiah L, et al.
Toxicol Pathol
. 2024 May;
52(2-3):88-98.
PMID: 38742644
Emerging urinary kidney safety biomarkers have been evaluated in recent years and have been shown to be superior to the serum parameters blood urea nitrogen (BUN) and creatinine (sCr) for...
4.
Zimmerman D, Hardgrove E, Sullivan S, Mitchell S, Kambale E, Nziza J, et al.
Sci Rep
. 2023 Apr;
13(1):5675.
PMID: 37029156
Ebola virus is highly lethal for great apes. Estimated mortality rates up to 98% have reduced the global gorilla population by approximately one-third. As mountain gorillas (Gorilla beringei beringei) are...
5.
Morozov I, P Monath T, Meekins D, Trujillo J, Sunwoo S, Urbaniak K, et al.
Emerg Microbes Infect
. 2021 Mar;
10(1):651-663.
PMID: 33719915
The recent impact of Ebola virus disease (EVD) on public health in Africa clearly demonstrates the need for a safe and efficacious vaccine to control outbreaks and mitigate its threat...
6.
Vlasakova K, Troth S, Sistare F, Glaab W
Toxicol Pathol
. 2020 Jul;
48(5):633-648.
PMID: 32633702
To date, there has been very little published data evaluating the performance of novel urinary kidney biomarkers in nonhuman primates (NHPs). To assess the biomarker performance and characterize the corresponding...
7.
Hukkanen R, Dybdal N, Tripathi N, Turner P, Troth S
Toxicol Pathol
. 2019 Oct;
47(7):789-798.
PMID: 31648619
Pathologists are trained medical professionals with special expertise in diagnostics, research, and pathophysiology. In these roles, pathologists are well qualified and positioned to engage in conversations about animal use replacement,...
8.
Sellers R, Nelson K, Bennet B, Wolf J, Tripathi N, Chamanza R, et al.
Toxicol Pathol
. 2019 Oct;
48(2):257-276.
PMID: 31594486
The design and execution of toxicology studies supporting vaccine development have some unique considerations relative to those supporting traditional small molecules and biologics. A working group of the Society of...
9.
P Monath T, Fast P, Modjarrad K, Clarke D, Martin B, Fusco J, et al.
Vaccine X
. 2019 Aug;
1:100009.
PMID: 31384731
The Brighton Collaboration Viral Vector Vaccines Safety Working Group (V3SWG) was formed to evaluate the safety and characteristics of live, recombinant viral vector vaccines. A recent publication by the V3SWG...
10.
Patrick D, Troth S
Toxicol Pathol
. 2019 Jul;
47(5):574-576.
PMID: 31303126
In the article "Opinion on Designation of Adverse and Nonadverse Histopathological Findings in Toxicity Studies: The Pathologist's Dilemma," the authors Gopinath and Mowat provide a framework for designation of adversity...