Sean D Stowe
Overview
Explore the profile of Sean D Stowe including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
124
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Recent Articles
1.
Milton M, Draughn G, Bobay B, Stowe S, Olson A, Feldmann E, et al.
J Mol Biol
. 2019 Sep;
432(2):343-357.
PMID: 31493408
Bacteria have developed numerous protection strategies to ensure survival in harsh environments, with perhaps the most robust method being the formation of a protective biofilm. In biofilms, bacterial cells are...
2.
Stowe S, Thompson R, Peng L, Su Z, Blackledge M, Draughn G, et al.
Curr Drug Deliv
. 2014 Oct;
12(2):223-30.
PMID: 25348099
Acinetobacter baumannii has quickly become one of the most insidious and prevalent nosocomial infections. Recently, the reverse-amide class of 2-aminoimidazole compounds (RA-2AI) was found both to prevent A. baumannii biofilm...
3.
Stowe S, Olson A, Losick R, Cavanagh J
Biomol NMR Assign
. 2013 Mar;
8(1):155-8.
PMID: 23475644
Bacillus subtilis is a soil-dwelling Gram-positive bacterial species that has been extensively studied as a model of biofilm formation and stress-induced cellular differentiation. The tetrameric protein, SinR, has been identified...
4.
Thompson R, Bobay B, Stowe S, Olson A, Peng L, Su Z, et al.
Biochemistry
. 2012 Nov;
51(49):9776-8.
PMID: 23186243
2-Aminoimidazoles (2AIs) have been documented to disrupt bacterial protection mechanisms, including biofilm formation and genetically encoded antibiotic resistance traits. Using Acinetobacter baumannii, we provide initial insight into the mechanism of...
5.
Stowe S, Tucker A, Thompson R, Piper A, Richards J, Rogers S, et al.
Drug Chem Toxicol
. 2012 Feb;
35(3):310-5.
PMID: 22292413
Biofilm formation is a ubiquitous bacterial defense mechanism and has been shown to be a primary element in the antibiotic resistance of many human diseases, especially in the case of...
6.
Stowe S, Richards J, Tucker A, Thompson R, Melander C, Cavanagh J
Mar Drugs
. 2011 Nov;
9(10):2010-2035.
PMID: 22073007
Bacterial biofilms are surface-attached communities of microorganisms that are protected by an extracellular matrix of biomolecules. In the biofilm state, bacteria are significantly more resistant to external assault, including attack...
7.
Richards J, Reyes S, Stowe S, Tucker A, Ballard T, Mathies L, et al.
J Med Chem
. 2009 Sep;
52(15):4582-5.
PMID: 19719234
The synthesis and antibiofilm activities of sulfonamide, urea, and thiourea oroidin analogues are described. The most active derivative was able to selectively inhibit P. aeruginosa biofilm development and is also...