Sean D Stocker
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Explore the profile of Sean D Stocker including associated specialties, affiliations and a list of published articles.
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75
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1636
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Recent Articles
11.
Stocker S, Wenner M, Farquhar W, Browning K
Hypertension
. 2021 Nov;
79(1):139-149.
PMID: 34809435
Neurons in the organum vasculosum of the lamina terminalis (OVLT) sense extracellular NaCl and angiotensin II concentrations to regulate body fluid homeostasis and arterial blood pressure. Lesion of the anteroventral...
12.
DeLalio L, Stocker S
J Neurophysiol
. 2021 Jul;
126(2):668-679.
PMID: 34259043
Activation of renal sensory nerves by chemo- and mechanosensitive stimuli produces changes in efferent sympathetic nerve activity (SNA) and arterial blood pressure (ABP). Anesthesia and sex influence autonomic function and...
13.
Galley J, Hahn S, Miller M, Durgin B, Jackson E, Stocker S, et al.
Br J Pharmacol
. 2021 May;
179(11):2490-2504.
PMID: 33963547
Background And Purpose: Reduced renal blood flow triggers activation of the renin-angiotensin-aldosterone system (RAAS) leading to renovascular hypertension. Renal vascular smooth muscle expression of the NO receptor, soluble GC (sGC),...
14.
DeLalio L, Stocker S
Am J Physiol Heart Circ Physiol
. 2020 Nov;
320(1):H117-H132.
PMID: 33216622
Elevated renal afferent nerve (ARNA) activity or dysfunctional reno-renal reflexes via altered ARNA sensitivity contribute to hypertension and chronic kidney disease. These nerves contain mechano- and chemosensitive fibers that respond...
15.
Watso J, Robinson A, Babcock M, Migdal K, Witman M, Wenner M, et al.
Physiol Rep
. 2020 Sep;
8(18):e14581.
PMID: 32965797
Older adults have reduced fluid intake and impaired body fluid and electrolyte regulation. Older female adults exhibit exaggerated exercise blood pressure (BP) responses, which is associated with an increased risk...
16.
Rush B, Bondi C, Stocker S, Barry K, Small S, Ong J, et al.
Kidney Int
. 2020 Aug;
99(1):102-116.
PMID: 32818518
The nuclear factor erythroid 2-related factor 2 (Nrf2) pathway upregulates key cellular defenses. Clinical trials are utilizing pharmacologic Nrf2 inducers such as bardoxolone methyl to treat chronic kidney disease, but...
17.
Chen Q, Yu J, Rush B, Stocker S, Tan R, Kim K
Kidney Int
. 2020 Jul;
98(2):355-365.
PMID: 32600826
Acute kidney injury (AKI) is a risk factor for the development of chronic kidney disease (CKD). One mechanism for this phenomenon is renal microvascular rarefaction and subsequent chronic impairment in...
18.
DeLalio L, Sved A, Stocker S
Can J Cardiol
. 2020 May;
36(5):712-720.
PMID: 32389344
The sympathetic nervous system plays a pivotal role in the long-term regulation of arterial blood pressure through the ability of the central nervous system to integrate neurohumoral signals and differentially...
19.
DeLalio L, Hahn S, Katayama P, Wenner M, Farquhar W, Straub A, et al.
Am J Physiol Heart Circ Physiol
. 2020 Apr;
318(5):H1346-H1355.
PMID: 32302491
Renovascular hypertension is characterized by activation of the renin-angiotensin-aldosterone system, blunted natriuretic responses, and elevated sympathetic nerve activity. Excess dietary salt intake exaggerates arterial blood pressure (ABP) in multiple models...
20.
The Impact of High Dietary Sodium Consumption on Blood Pressure Variability in Healthy, Young Adults
Migdal K, Babcock M, Robinson A, Watso J, Wenner M, Stocker S, et al.
Am J Hypertens
. 2020 Feb;
33(5):422-429.
PMID: 32006422
Background: High sodium (Na+) intake augments blood pressure variability (BPV) in normotensive rodents, without changes in resting blood pressure (BP). Augmented BPV is associated with end-organ damage and cardiovascular morbidity....