Glenn M Toney
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Explore the profile of Glenn M Toney including associated specialties, affiliations and a list of published articles.
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68
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1677
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Recent Articles
1.
Chivers S, Andrade M, Hammack R, Shannonhouse J, Gomez R, Zhang Y, et al.
Sci Signal
. 2024 Jul;
17(847):eadn8936.
PMID: 39078919
Obstructive sleep apnea (OSA) is a prevalent sleep disorder that is associated with increased incidence of chronic musculoskeletal pain. We investigated the mechanism of this association in a mouse model...
2.
Yamaguchi J, Andrade M, Truong T, Toney G
J Neurosci
. 2023 Dec;
44(7).
PMID: 38154957
The hypothalamic paraventricular nucleus (PVN) is strongly inhibited by γ-aminobutyric acid (GABA) from the surrounding peri-nuclear zone (PNZ). Because glutamate mediates fast excitatory transmission and is substrate for GABA synthesis,...
3.
Hammack R, Fischer V, Andrade M, Toney G
Learn Mem
. 2023 Oct;
30(10):250-259.
PMID: 37802546
Fear memory formation and recall are highly regulated processes, with the central amygdala (CeA) contributing to fear memory-related behaviors. We recently reported that a remote fear memory engram is resident...
4.
Hammack R, Fischer V, Andrade M, Toney G
Front Neural Circuits
. 2023 May;
17:1167825.
PMID: 37180762
Introduction: Threatening environmental cues often generate enduring fear memories, but how these are formed and stored remains actively investigated. Recall of a recent fear memory is thought to reflect reactivation...
5.
Strain M, Espinoza L, Fedorchak S, Littlejohn E, Andrade M, Toney G, et al.
Sci Rep
. 2023 Apr;
13(1):6550.
PMID: 37085567
High fat diet (HFD) promotes cardiovascular disease and blunted cardiac vagal regulation. Temporal onset of loss of cardiac vagal control and its underlying mechanism are presently unclear. We tested our...
6.
Jia S, Rybalchenko N, Kunwar K, Farmer Jr G, Little J, Toney G, et al.
J Neurophysiol
. 2022 Nov;
128(6):1383-1394.
PMID: 36321700
Chronic intermittent hypoxia (CIH), an animal model of sleep apnea, has been shown to alter the activity of second-order chemoreceptor neurons in the caudal nucleus of the solitary tract (cNTS)....
7.
Mourao A, Shimoura C, Andrade M, Truong T, Pedrino G, Toney G
Am J Physiol Heart Circ Physiol
. 2021 Aug;
321(3):H580-H591.
PMID: 34355986
Tumor necrosis factor-α (TNFα) in the hypothalamic paraventricular nucleus (PVN) contributes to increased sympathetic nerve activity (SNA) in cardiovascular disease models, but mechanisms are incompletely understood. As previously reported, bilateral...
8.
Brackley A, Toney G
J Pharmacol Exp Ther
. 2021 May;
378(2):96-107.
PMID: 33990416
Opioid overdose intervention by naloxone, a high affinity receptor antagonist, reverses opioid-induced respiratory depression (OIRD) and analgesia by displacing opioids. Systemic naloxone stimulates release of the hypothalamic neuropeptide oxytocin, which...
9.
Levi D, Wyrosdic J, Hicks A, Andrade M, Toney G, Prager-Khoutorsky M, et al.
Cell Rep
. 2021 Mar;
34(11):108866.
PMID: 33730577
High dietary salt increases arterial pressure partly through activation of magnocellular neurosecretory cells (MNC) that secrete the antidiuretic and vasoconstrictor hormone vasopressin (VP) into the circulation. Here, we show that...
10.
Brackley A, Andrade M, Toney G
J Physiol
. 2020 May;
598(15):3239-3257.
PMID: 32415789
Key Points: Sleep apnoea increases susceptibility to opioid-induced respiratory depression (OIRD). Endogenous opioids are implicated as a contributing factor in sleep apnoea. Rats exposed to sleep-phase chronic intermittent hypercapnic hypoxia...