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Scott Tighe

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Articles 33
Citations 1767
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Recent Articles
1.
Chander A, Teixeira M, Singh N, Williams M, Parker C, Leo P, et al.
Sci Rep . 2024 May; 14(1):12249. PMID: 38806503
Members of the family Trichomeriaceae, belonging to the Chaetothyriales order and the Ascomycota phylum, are known for their capability to inhabit hostile environments characterized by extreme temperatures, oligotrophic conditions, drought,...
2.
Simpson A, Tighe S, Wong S, Leo P, Parker C, Chander A, et al.
J Biomol Tech . 2023 Nov; 34(3). PMID: 37969875
The rapid assessment of microbiomes from ultra-low biomass environments such as cleanrooms or hospital operating rooms has a number of applications for human health and spacecraft manufacturing. Current techniques often...
3.
Leo P, Onofri S, Zucconi L, Selbmann L, Turchetti B, Buzzini P, et al.
Microbiol Resour Announc . 2023 Sep; 12(10):e0038823. PMID: 37754785
The draft genomes of five strains were sequenced using MinION and annotated using Funannotate pipeline. Phylogenetic and genomic analyses were performed to provide their genetic relationships, diversity, and potential functional...
4.
Bizic M, Brad T, Ionescu D, Barbu-Tudoran L, Zoccarato L, Aerts J, et al.
ISME J . 2022 Dec; 17(3):340-353. PMID: 36528730
Thiovulum spp. (Campylobacterota) are large sulfur bacteria that form veil-like structures in aquatic environments. The sulfidic Movile Cave (Romania), sealed from the atmosphere for ~5 million years, has several aqueous...
5.
Ramos-Nino M, Fitzpatrick D, Eckstrom K, Tighe S, Dragon J, Cheetham S
Animals (Basel) . 2021 Jun; 11(6). PMID: 34072244
Bats are capable of asymptomatically carrying a diverse number of microorganisms, including human pathogens, due to their unique immune system. Because of the close contact between bats and humans, there...
6.
Scharer C, Fortner K, Dragon J, Tighe S, Boss J, Budd R
Immunohorizons . 2020 Oct; 4(10):679-687. PMID: 33097564
Systemic lupus erythematosus (SLE) is characterized by increased DNA demethylation in T cells, although it is unclear whether this occurs primarily in a subset of SLE T cells. The process...
7.
Parker C, Singh N, Tighe S, Blachowicz A, Wood J, Seuylemezian A, et al.
mSystems . 2020 Oct; 5(5). PMID: 33024053
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019, is a respiratory virus primarily transmitted person to person through inhalation of droplets or aerosols, laden...
8.
Bruce E, Huang M, Perchetti G, Tighe S, Laaguiby P, Hoffman J, et al.
PLoS Biol . 2020 Oct; 18(10):e3000896. PMID: 33006983
The ongoing COVID-19 pandemic has created an unprecedented need for rapid diagnostic testing. The World Health Organization (WHO) recommends a standard assay that includes an RNA extraction step from a...
9.
Box A, DeLay M, Tighe S, Chittur S, Bergeron A, Cochran M, et al.
J Biomol Tech . 2020 Sep; 31(3):100-111. PMID: 32982601
Cell sorting is a commonly used technology to isolate highly purified cell populations for downstream applications. Because the sorted cells are destined for further analysis, , gene expression assays or...
10.
Urbaniak C, Wong S, Tighe S, Arumugam A, Liu B, Parker C, et al.
Front Microbiol . 2020 Sep; 11:1909. PMID: 32973700
NASA has made great strides in the past five years to develop a suite of instruments for the International Space Station in order to perform molecular biology in space. However,...