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Scott Terhune

Explore the profile of Scott Terhune including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 207
Followers 0
Related Specialties
Oncology
Microbiology
Molecular Biology
Top 10 Co-Authors
Justin Reitsma
Sebastian Zeltzer
Felicia Goodrum
Jason Buehler
Michael A Rak
Belen Molina
Marja T Nevalainen
Patricia Zagallo
Mahadevaiah Umashankar
Alfredo S Colina
Published In
J Virol
Methods Mol Biol
PLoS Pathog
Front Mol Med
Cancers (Basel)
Affiliations
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Recent Articles
1.
Current advances in experimental and computational approaches to enhance CAR T cell manufacturing protocols and improve clinical efficacy
Colina A, Shah V, Shah R, Kozlik T, Dash R, Terhune S, et al.
Front Mol Med . 2024 Aug; 4:1310002. PMID: 39086435
Since the FDA's approval of chimeric antigen receptor (CAR) T cells in 2017, significant improvements have been made in the design of chimeric antigen receptor constructs and in the manufacturing...
2.
Method to Study Adaptive NK Cells Following MCMV Infections
Khalil M, Mei A, Hashemi E, Wang D, Schumacher M, Terhune S, et al.
Methods Mol Biol . 2022 Mar; 2463:195-204. PMID: 35344176
Immunological memory is a fundamental feature of the adaptive immune system that protects the host from recurrent infections from pathogens. Natural killer (NK) cells are a predominant member of the...
3.
Prospects for Clinical Development of Stat5 Inhibitor IST5-002: High Transcriptomic Specificity in Prostate Cancer and Low Toxicity In Vivo
Maranto C, Udhane V, Jia J, Verma R, Muller-Newen G, LaViolette P, et al.
Cancers (Basel) . 2020 Nov; 12(11). PMID: 33217941
Stat5 is of significant interest in the search for new therapeutics for prostate cancer (PC) and hematopoietic disorders. We evaluated the transcriptomic specificity of the Stat5a/b inhibitor IST5-002 (IST5) in...
4.
Erratum for Rak et al., "Human Cytomegalovirus UL135 Interacts with Host Adaptor Proteins To Regulate Epidermal Growth Factor Receptor and Reactivation from Latency"
Rak M, Buehler J, Zeltzer S, Reitsma J, Molina B, Terhune S, et al.
J Virol . 2020 Mar; 94(7). PMID: 32184335
No abstract available.
5.
Human Cytomegalovirus UL135 Interacts with Host Adaptor Proteins To Regulate Epidermal Growth Factor Receptor and Reactivation from Latency
Rak M, Buehler J, Zeltzer S, Reitsma J, Molina B, Terhune S, et al.
J Virol . 2018 Aug; 92(20). PMID: 30089695
Human cytomegalovirus, HCMV, is a betaherpesvirus that establishes a lifelong latent infection in its host that is marked by recurrent episodes of reactivation. The molecular mechanisms by which the virus...
6.
Opposing Regulation of the EGF Receptor: A Molecular Switch Controlling Cytomegalovirus Latency and Replication
Buehler J, Zeltzer S, Reitsma J, Petrucelli A, Umashankar M, Rak M, et al.
PLoS Pathog . 2016 May; 12(5):e1005655. PMID: 27218650
Herpesviruses persist indefinitely in their host through complex and poorly defined interactions that mediate latent, chronic or productive states of infection. Human cytomegalovirus (CMV or HCMV), a ubiquitous β-herpesvirus, coordinates...
7.
Human cytomegalovirus UL38 protein blocks apoptosis
Terhune S, Torigoi E, Moorman N, Silva M, Qian Z, Shenk T, et al.
J Virol . 2007 Jan; 81(7):3109-23. PMID: 17202209
Apoptosis is an innate cellular defense response to viral infection. The slow-replicating human cytomegalovirus (HCMV) blocks premature death of host cells prior to completion of the infection cycle. In this...