Scott T Magness
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Explore the profile of Scott T Magness including associated specialties, affiliations and a list of published articles.
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77
Citations
4036
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Recent Articles
1.
Pioneering a New Frontier: Modeling the Epithelial-immune Cell Axis Using Human Intestinal Organoids
Magness S
Cell Mol Gastroenterol Hepatol
. 2025 Jan;
:101461.
PMID: 39864812
No abstract available.
2.
Rose E, Simon J, Gomez-Martinez I, Magness S, Odle J, Blikslager A, et al.
Am J Physiol Gastrointest Liver Physiol
. 2025 Jan;
328(3):G182-G196.
PMID: 39853303
Intestinal ischemic injury damages the epithelial barrier and predisposes patients to life-threatening sepsis unless that barrier is rapidly restored. There is an age dependency in intestinal recovery in that neonates...
3.
Burclaff J, Magness S
Bio Protoc
. 2024 Nov;
14(22):e5116.
PMID: 39600970
Primary human intestinal stem cells (ISCs) can be cultured and passaged indefinitely as two-dimensional monolayers grown on soft collagen. Culturing ISCs as monolayers enables easy access to the luminal side...
4.
Ghimire J, Collins M, Snarski P, King A, Ruiz E, Iftikhar R, et al.
Gastroenterology
. 2024 Sep;
168(2):286-299.e6.
PMID: 39299402
Background & Aims: The obesity epidemic is associated with increased colon cancer progression. As lipid droplets (LDs) fuel tumor growth, we aimed to determine the significance of diacyltransferases (diacylglycerol o-acyltransferases...
5.
Marsh A, Yaya A, Ng S, Chandrashekhar K, Roach J, Magness S, et al.
Gut Microbiome (Camb)
. 2024 Sep;
1:e4.
PMID: 39296723
Knowledge of the intra-individual spatial and regional distribution of intestinal microbial populations is essential to understand gut host-microbial interactions. In this study, we performed a compositional analysis of luminal and...
6.
Rusch G, Wang J, Breau K, Kilgour K, Gilleskie G, Keele J, et al.
bioRxiv
. 2024 Jul;
PMID: 38979374
Process Analytical Technologies (PAT) used to monitor and control manufacturing processes are crucial for efficient and automated bioprocessing, which is in congruence with lights-off-manufacturing and Industry 4.0 initiatives. As biomanufacturing...
7.
Rose E, Simon J, Gomez-Martinez I, Magness S, Odle J, Blikslager A, et al.
bioRxiv
. 2024 Jul;
PMID: 38979337
New & Noteworthy: These studies validate an approach to identify and predict upstream regulation of restituting epithelium in a unique pig intestinal ischemic injury model. Identification of potential molecular mediators...
8.
Cotton M, Ariel P, Chen K, Walcott V, Dixit M, Breau K, et al.
Sci Rep
. 2024 Jul;
14(1):15195.
PMID: 38956443
The intestinal epithelium dynamically controls cell cycle, yet no experimental platform exists for directly analyzing cell cycle phases in non-immortalized human intestinal epithelial cells (IECs). Here, we present two reporters...
9.
Ziegler A, Caldwell M, Craig S, Hellstrom E, Sheridan A, Touvron M, et al.
Am J Physiol Gastrointest Liver Physiol
. 2023 Dec;
326(3):G228-G246.
PMID: 38147796
Ischemic damage to the intestinal epithelial barrier, such as in necrotizing enterocolitis or small intestinal volvulus, is associated with higher mortality rates in younger patients. We have recently reported a...
10.
An in vitro platform for quantifying cell cycle phase lengths in primary human intestinal stem cells
Cotton M, Ariel P, Chen K, Walcott V, Dixit M, Breau K, et al.
bioRxiv
. 2023 Oct;
PMID: 37873351
Background And Aims: The intestinal epithelium exhibits dynamic control of cell cycle phase lengths, yet no experimental platform exists for directly analyzing cell cycle phases in living human intestinal stem...