Ian A Williamson
Overview
Explore the profile of Ian A Williamson including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
379
Followers
0
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Recent Articles
1.
Gomez-Martinez I, Bliton R, Breau K, Czerwinski M, Williamson I, Wen J, et al.
Cell Mol Gastroenterol Hepatol
. 2022 Apr;
14(2):409-434.
PMID: 35489715
Background & Aims: Fatty acid oxidation by absorptive enterocytes has been linked to the pathophysiology of type 2 diabetes, obesity, and dyslipidemia. Caco-2 and organoids have been used to study...
2.
Zwarycz B, Gracz A, Rivera K, Williamson I, Samsa L, Starmer J, et al.
Cell Mol Gastroenterol Hepatol
. 2018 Oct;
7(1):1-17.
PMID: 30364840
Background & Aims: Crohn's disease is an inflammatory bowel disease that affects the ileum and is associated with increased cytokines. Although interleukin (IL)6, IL17, IL21, and IL22 are increased in...
3.
Samsa L, Williamson I, Magness S
Methods Mol Biol
. 2018 Sep;
1842:139-166.
PMID: 30196407
Regeneration of intestinal epithelium is fueled by a heterogeneous population of rapidly proliferating stem cells (ISCs) found in the base of the small intestine and colonic crypts. ISCs populations can...
4.
Williamson I, Arnold J, Samsa L, Gaynor L, DiSalvo M, Cocchiaro J, et al.
Cell Mol Gastroenterol Hepatol
. 2018 Aug;
6(3):301-319.
PMID: 30123820
Background & Aims: The human gut microbiota is becoming increasingly recognized as a key factor in homeostasis and disease. The lack of physiologically relevant in vitro models to investigate host-microbe...
5.
Smith N, Swain J, Davies P, Gallagher A, Parappilly M, Beach C, et al.
Cell Mol Gastroenterol Hepatol
. 2018 Jun;
6(1):79-96.
PMID: 29928673
Background & Aims: Continual renewal of the intestinal epithelium is dependent on active- and slow-cycling stem cells that are confined to the crypt base. Tight regulation of these stem cell...
6.
Wang Y, DiSalvo M, Gunasekara D, Dutton J, Proctor A, Lebhar M, et al.
Cell Mol Gastroenterol Hepatol
. 2017 Dec;
4(1):165-182.e7.
PMID: 29204504
Background & Aims: Three-dimensional organoid culture has fundamentally changed the in vitro study of intestinal biology enabling novel assays; however, its use is limited because of an inaccessible luminal compartment...
7.
Gracz A, Williamson I, Roche K, Johnston M, Wang F, Wang Y, et al.
Nat Cell Biol
. 2015 Feb;
17(3):340-9.
PMID: 25664616
Stem cells reside in 'niches', where support cells provide critical signalling for tissue renewal. Culture methods mimic niche conditions and support the growth of stem cells in vitro. However, current...