Scott T Dougan
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Explore the profile of Scott T Dougan including associated specialties, affiliations and a list of published articles.
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14
Citations
657
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Recent Articles
1.
Tseng W, Munisha M, Gutierrez J, Dougan S
Adv Exp Med Biol
. 2016 Dec;
953:307-381.
PMID: 27975275
The process of germ layer formation is a universal feature of animal development. The germ layers separate the cells that produce the internal organs and tissues from those that produce...
2.
Lindy A, Basehore M, Munisha M, Williams A, Friez M, Writzl K, et al.
Am J Med Genet A
. 2016 Mar;
170(6):1573-9.
PMID: 27028100
Thanatophoric dysplasia is a type of short-limbed neonatal dwarfism that is usually lethal in the perinatal period. It is characterized by short limbs, a narrow, bell-shaped thorax, macrocephaly with a...
3.
Sun Y, Tseng W, Fan X, Ball R, Dougan S
Dev Cell
. 2014 Feb;
28(3):322-34.
PMID: 24525188
In vertebrates, extraembryonic tissues can act as signaling centers that impose a reproducible pattern of cell types upon the embryo. Here, we show that the zebrafish yolk syncytial layer (YSL)...
4.
Sun Y, Wloga D, Dougan S
Methods Mol Biol
. 2011 Aug;
770:139-84.
PMID: 21805264
Due to the powerful combination of genetic and embryological techniques, the teleost fish Danio rerio has emerged in the last decade as an important model organism for the study of...
5.
Akella J, Wloga D, Kim J, Starostina N, Lyons-Abbott S, Morrissette N, et al.
Nature
. 2010 Sep;
467(7312):218-22.
PMID: 20829795
In most eukaryotic cells, subsets of microtubules are adapted for specific functions by post-translational modifications (PTMs) of tubulin subunits. Acetylation of the epsilon-amino group of K40 on alpha-tubulin is a...
6.
Wloga D, Webster D, Rogowski K, Bre M, Levilliers N, Jerka-Dziadosz M, et al.
Dev Cell
. 2009 Jun;
16(6):867-76.
PMID: 19531357
In most ciliated cell types, tubulin is modified by glycylation, a posttranslational modification of unknown function. We show that the TTLL3 proteins act as tubulin glycine ligases with chain-initiating activity....
7.
Moss L, Monette M, Jaso-Friedmann L, Leary 3rd J, Dougan S, Krunkosky T, et al.
Dev Comp Immunol
. 2009 May;
33(10):1077-87.
PMID: 19477195
Coelomic cavity (CC) cells of mature zebrafish harvested by lavage with media or trypsin-EDTA contained 0.80-1.20 x 10(5) and 2.0-3.5 x 10(5) cells, respectively. Media lavage was composed of granulocytes...
8.
Webster D, Teo C, Sun Y, Wloga D, Gay S, Klonowski K, et al.
BMC Dev Biol
. 2009 Apr;
9:28.
PMID: 19383152
Background: The post-translational addition of the monosaccharide O-linked beta-N-acetylglucosamine (O-GlcNAc) regulates the activity of a wide variety of nuclear and cytoplasmic proteins. The enzymes O-GlcNAc Transferase (Ogt) and O-GlcNAcase (Oga)...
9.
Fan X, Dougan S
Dev Genes Evol
. 2007 Nov;
217(11-12):807-13.
PMID: 17992538
Because of an extra whole-genome duplication, zebrafish and other teleosts have two copies of genes that are present in a single copy in tetrapod genomes. Some zebrafish genes, however, are...
10.
Fan X, Hagos E, Xu B, Sias C, Kawakami K, Burdine R, et al.
Dev Biol
. 2007 Sep;
310(2):363-78.
PMID: 17850782
In many vertebrates, extra-embryonic tissues are important signaling centers that induce and pattern the germ layers. In teleosts, the mechanism by which the extra-embryonic yolk syncytial layer (YSL) patterns the...