Scott McCuine
Overview
Explore the profile of Scott McCuine including associated specialties, affiliations and a list of published articles.
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7
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1570
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Recent Articles
1.
Mazzoni E, Mahony S, Peljto M, Patel T, Thornton S, McCuine S, et al.
Nat Neurosci
. 2013 Aug;
16(9):1191-1198.
PMID: 23955559
Hox genes controlling motor neuron subtype identity are expressed in rostrocaudal patterns that are spatially and temporally collinear with their chromosomal organization. Here we demonstrate that Hox chromatin is subdivided...
2.
Mahony S, Mazzoni E, McCuine S, Young R, Wichterle H, Gifford D
Genome Biol
. 2011 Jan;
12(1):R2.
PMID: 21232103
Background: Among its many roles in development, retinoic acid determines the anterior-posterior identity of differentiating motor neurons by activating retinoic acid receptor (RAR)-mediated transcription. RAR is thought to bind the...
3.
Rahl P, Lin C, Seila A, Flynn R, McCuine S, Burge C, et al.
Cell
. 2010 May;
141(3):432-45.
PMID: 20434984
Recruitment of the RNA polymerase II (Pol II) transcription initiation apparatus to promoters by specific DNA-binding transcription factors is well recognized as a key regulatory step in gene expression. We...
4.
Vokes S, Ji H, McCuine S, Tenzen T, Giles S, Zhong S, et al.
Development
. 2007 Apr;
134(10):1977-89.
PMID: 17442700
Sonic hedgehog (Shh) acts as a morphogen to mediate the specification of distinct cell identities in the ventral neural tube through a Gli-mediated (Gli1-3) transcriptional network. Identifying Gli targets in...
5.
Workman C, Mak H, McCuine S, Tagne J, Agarwal M, Ozier O, et al.
Science
. 2006 May;
312(5776):1054-9.
PMID: 16709784
Failure of cells to respond to DNA damage is a primary event associated with mutagenesis and environmental toxicity. To map the transcriptional network controlling the damage response, we measured genomewide...
6.
Yeang C, Mak H, McCuine S, Workman C, Jaakkola T, Ideker T
Genome Biol
. 2005 Jul;
6(7):R62.
PMID: 15998451
As genome-scale measurements lead to increasingly complex models of gene regulation, systematic approaches are needed to validate and refine these models. Towards this goal, we describe an automated procedure for...
7.
Sharan R, Suthram S, Kelley R, Kuhn T, McCuine S, Uetz P, et al.
Proc Natl Acad Sci U S A
. 2005 Feb;
102(6):1974-9.
PMID: 15687504
To elucidate cellular machinery on a global scale, we performed a multiple comparison of the recently available protein-protein interaction networks of Caenorhabditis elegans, Drosophila melanogaster, and Saccharomyces cerevisiae. This comparison...