Scott M OGrady
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Explore the profile of Scott M OGrady including associated specialties, affiliations and a list of published articles.
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54
Citations
1069
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Recent Articles
11.
Zaidman N, Panoskaltsis-Mortari A, OGrady S
J Physiol
. 2017 May;
595(14):4631-4645.
PMID: 28481415
Key Points: Hydrocortisone (HC) is required for activation of large-conductance Ca -activated K current (BK) by purinergic receptor agonists. HC reduces insertion of the stress-regulated exon (STREX) in the KCNMA1...
12.
Zaidman N, OGrady K, Patil N, Milavetz F, Maniak P, Kita H, et al.
Am J Physiol Cell Physiol
. 2017 Apr;
313(1):C68-C79.
PMID: 28446427
Aeroallergens produced by can elicit life-threatening exacerbations of asthma in patients sensitized to this fungus. In this study, the effect of on ion transport mechanisms underlying mucociliary clearance and airway...
13.
Cero C, Razzoli M, Han R, Sahu B, Patricelli J, Guo Z, et al.
Mol Metab
. 2017 Jan;
6(1):148-158.
PMID: 28123945
Objectives: Obesity is characterized by excessive fat mass and is associated with serious diseases such as type 2 diabetes. Targeting excess fat mass by sustained lipolysis has been a major...
14.
Im J, Kim K, Yhee J, OGrady S, Nho R
Physiol Rep
. 2016 Dec;
4(21).
PMID: 27905295
Alternaria alternata is an allergenic fungus and known to cause an upper respiratory tract infection and asthma in humans with compromised immunity. Although A. alternata's effect on airway epithelial cells...
15.
Zaidman N, Panoskaltsis-Mortari A, OGrady S
Am J Physiol Cell Physiol
. 2016 Jun;
311(2):C225-36.
PMID: 27306366
Glucocorticoids strongly influence the mucosal-defense functions performed by the bronchial epithelium, and inhaled corticosteroids are critical in the treatment of patients with inflammatory airway diseases such as asthma, chronic obstructive...
16.
Peitzman E, Zaidman N, Maniak P, OGrady S
Am J Physiol Lung Cell Mol Physiol
. 2015 Nov;
310(1):L50-8.
PMID: 26566905
Carvedilol functions as a nonselective β-adrenergic receptor (AR)/α1-AR antagonist that is used for treatment of hypertension and heart failure. Carvedilol has been shown to function as an inverse agonist, inhibiting...
17.
Peitzman E, Zaidman N, Maniak P, OGrady S
Am J Physiol Cell Physiol
. 2015 Oct;
309(12):C847-55.
PMID: 26491049
Human airway epithelial cells express β-adrenergic receptors (β-ARs), which regulate mucociliary clearance by stimulating transepithelial anion transport and ciliary beat frequency. Previous studies using airway epithelial cells showed that stimulation...
18.
Krishna V, Roach E, Zaidman N, Panoskaltsis-Mortari A, Rotschafer J, OGrady S, et al.
PLoS One
. 2015 Sep;
10(9):e0138704.
PMID: 26384331
Interferons (IFNs) have been shown to inhibit influenza A virus (IAV) replication and play an essential role in controlling viral infection. Here we studied the kinetics and magnitude of induction...
19.
Jang S, Byun J, Jeon W, Choi S, Park J, Lee B, et al.
J Biol Chem
. 2015 Apr;
290(20):12547-57.
PMID: 25829491
It is widely known that ion channels are expressed in the plasma membrane. However, a few studies have suggested that several ion channels including voltage-gated K(+) (Kv) channels also exist...
20.
Itokazu Y, Pagano R, Schroeder A, OGrady S, Limper A, Marks D
Am J Physiol Cell Physiol
. 2014 Feb;
306(9):C819-30.
PMID: 24500283
Loss of cystic fibrosis transmembrane conductance regulator (CFTR) function reduces chloride secretion and increases sodium uptake, but it is not clear why CFTR mutation also results in progressive lung inflammation...