Peter J Maniak
Overview
Explore the profile of Peter J Maniak including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
165
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0
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Recent Articles
1.
Hayashi R, Srisomboon Y, Iijima K, Maniak P, Tei R, Kobayashi T, et al.
J Allergy Clin Immunol
. 2023 Nov;
153(3):793-808.e2.
PMID: 38000698
Background: Nonneuronal cells, including epithelial cells, can produce acetylcholine (ACh). Muscarinic ACh receptor antagonists are used clinically to treat asthma and other medical conditions; however, knowledge regarding the roles of...
2.
Srisomboon Y, Iijima K, Colwell M, Maniak P, Macchietto M, Faulk C, et al.
J Allergy Clin Immunol
. 2022 Oct;
151(2):494-508.e6.
PMID: 36306937
Background: Alternaria alternata and house dust mite exposure evokes IL-33 secretion from the airway epithelium, which functions as an alarmin to stimulate type 2 immunity. Extracellular DNA (eDNA) is also...
3.
Srisomboon Y, Ohkura N, Iijima K, Kobayashi T, Maniak P, Kita H, et al.
Int J Mol Sci
. 2021 Aug;
22(16).
PMID: 34445774
Polyethyleneimine (PEI) induced immune responses were investigated in human bronchial epithelial (hBE) cells and mice. PEI rapidly induced ATP release from hBE cells and pretreatment with glutathione (GSH) blocked the...
4.
Srisomboon Y, Squillace D, Maniak P, Kita H, OGrady S
J Physiol
. 2020 Feb;
598(10):1829-1845.
PMID: 32103508
Key Points: Alternaria aeroallergens induce the release of ATP from human bronchial epithelial (HBE) cells by activating a conductive pathway involving voltage-dependent anion channel-1 (VDAC-1) and by exocytosis of ATP...
5.
Srisomboon Y, Zaidman N, Maniak P, Deachapunya C, OGrady S
Am J Physiol Cell Physiol
. 2018 Jan;
314(5):C627-C639.
PMID: 29365273
The objective of this study was to determine the molecular identity of ion channels involved in K secretion by the mammary epithelium and to examine their regulation by purinoceptor agonists....
6.
Zaidman N, OGrady K, Patil N, Milavetz F, Maniak P, Kita H, et al.
Am J Physiol Cell Physiol
. 2017 Apr;
313(1):C68-C79.
PMID: 28446427
Aeroallergens produced by can elicit life-threatening exacerbations of asthma in patients sensitized to this fungus. In this study, the effect of on ion transport mechanisms underlying mucociliary clearance and airway...
7.
Peitzman E, Zaidman N, Maniak P, OGrady S
Am J Physiol Lung Cell Mol Physiol
. 2015 Nov;
310(1):L50-8.
PMID: 26566905
Carvedilol functions as a nonselective β-adrenergic receptor (AR)/α1-AR antagonist that is used for treatment of hypertension and heart failure. Carvedilol has been shown to function as an inverse agonist, inhibiting...
8.
Peitzman E, Zaidman N, Maniak P, OGrady S
Am J Physiol Cell Physiol
. 2015 Oct;
309(12):C847-55.
PMID: 26491049
Human airway epithelial cells express β-adrenergic receptors (β-ARs), which regulate mucociliary clearance by stimulating transepithelial anion transport and ciliary beat frequency. Previous studies using airway epithelial cells showed that stimulation...
9.
OGrady S, Patil N, Melkamu T, Maniak P, Lancto C, Kita H
J Physiol
. 2013 Jul;
591(18):4595-609.
PMID: 23858006
Exposure of human bronchial epithelial (HBE) cells from normal and asthmatic subjects to extracts from Alternaria alternata evoked a rapid and sustained release of ATP with greater efficacy observed in...
10.
Palmer M, Peitzman E, Maniak P, Sieck G, Prakash Y, OGrady S
J Physiol
. 2011 May;
589(Pt 14):3483-94.
PMID: 21606112
Human mammary epithelial (HME) cells express several P2Y receptor subtypes located in both apical and basolateral membranes. Apical UTP or ATP-γ-S stimulation of monolayers mounted in Ussing chambers evoked a...