Scott M OGrady
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Explore the profile of Scott M OGrady including associated specialties, affiliations and a list of published articles.
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54
Citations
1069
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Recent Articles
1.
Srisomboon Y, Tojima I, Iijima K, Kita H, OGrady S
J Allergy Clin Immunol
. 2025 Jan;
PMID: 39863058
Background: Environmental allergens induce the release of danger signals from the airway epithelium that trigger type 2 immune responses and promote airway inflammation. Objective: We investigated the role of allergen-stimulated...
2.
Hayashi R, Srisomboon Y, Iijima K, Maniak P, Tei R, Kobayashi T, et al.
J Allergy Clin Immunol
. 2023 Nov;
153(3):793-808.e2.
PMID: 38000698
Background: Nonneuronal cells, including epithelial cells, can produce acetylcholine (ACh). Muscarinic ACh receptor antagonists are used clinically to treat asthma and other medical conditions; however, knowledge regarding the roles of...
3.
OGrady S, Kita H
Am J Physiol Cell Physiol
. 2023 Oct;
325(5):C1369-C1386.
PMID: 37842751
Environmental allergens that interact with the airway epithelium can activate cellular stress pathways that lead to the release of danger signals known as alarmins. The mechanisms of alarmin release are...
4.
Srisomboon Y, Iijima K, Colwell M, Maniak P, Macchietto M, Faulk C, et al.
J Allergy Clin Immunol
. 2022 Oct;
151(2):494-508.e6.
PMID: 36306937
Background: Alternaria alternata and house dust mite exposure evokes IL-33 secretion from the airway epithelium, which functions as an alarmin to stimulate type 2 immunity. Extracellular DNA (eDNA) is also...
5.
Srisomboon Y, Ohkura N, Iijima K, Kobayashi T, Maniak P, Kita H, et al.
Int J Mol Sci
. 2021 Aug;
22(16).
PMID: 34445774
Polyethyleneimine (PEI) induced immune responses were investigated in human bronchial epithelial (hBE) cells and mice. PEI rapidly induced ATP release from hBE cells and pretreatment with glutathione (GSH) blocked the...
6.
Srisomboon Y, Squillace D, Maniak P, Kita H, OGrady S
J Physiol
. 2020 Feb;
598(10):1829-1845.
PMID: 32103508
Key Points: Alternaria aeroallergens induce the release of ATP from human bronchial epithelial (HBE) cells by activating a conductive pathway involving voltage-dependent anion channel-1 (VDAC-1) and by exocytosis of ATP...
7.
OGrady S
Am J Physiol Cell Physiol
. 2018 Oct;
316(1):C16-C32.
PMID: 30303690
Mucociliary clearance is critically important in protecting the airways from infection and from the harmful effects of smoke and various inspired substances known to induce oxidative stress and persistent inflammation....
8.
Ha S, Dileepan M, Ge X, Kang B, Greenberg Y, Rao A, et al.
J Allergy Clin Immunol
. 2018 Mar;
142(6):1808-1817.e3.
PMID: 29522849
Background: Altered epithelial physical and functional barrier properties along with T1/T2 immune dysregulation are features of allergic asthma. Regulation of junction proteins to improve barrier function of airway epithelial cells...
9.
Srisomboon Y, Zaidman N, Maniak P, Deachapunya C, OGrady S
Am J Physiol Cell Physiol
. 2018 Jan;
314(5):C627-C639.
PMID: 29365273
The objective of this study was to determine the molecular identity of ion channels involved in K secretion by the mammary epithelium and to examine their regulation by purinoceptor agonists....
10.