Scott M Laster
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Explore the profile of Scott M Laster including associated specialties, affiliations and a list of published articles.
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17
Citations
150
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Recent Articles
1.
Cortes L, Brodsky D, Chen C, Pridgen T, Odle J, Snider D, et al.
Front Allergy
. 2022 Dec;
3:1029184.
PMID: 36452260
Eosinophilic esophagitis (EoE) is a chronic allergy-mediated condition with an increasing incidence in both children and adults. Despite EoE's strong impact on human health and welfare, there is a large...
2.
Mottin M, Caesar L, Brodsky D, Mesquita N, de Oliveira K, Noske G, et al.
Bioorg Chem
. 2022 Feb;
120:105649.
PMID: 35124513
Zika virus (ZIKV) is a dangerous human pathogen and no antiviral drugs have been approved to date. The chalcones are a group of small molecules that are found in a...
3.
Plundrich N, Smith A, Borst L, Snider D, Kaser T, Dellon E, et al.
Clin Exp Allergy
. 2019 Nov;
50(1):95-104.
PMID: 31702085
Background: Esophagitis with eosinophilia, inflammation, and fibrosis represent a chronic condition in humans with food allergies. Objective: In this investigation, we asked whether esophagitis with an eosinophilic component is observed...
4.
Gulledge T, Collette N, Mackey E, Johnstone S, Moazami Y, Todd D, et al.
J Ethnopharmacol
. 2017 Oct;
212:166-174.
PMID: 29042288
Ethnopharmacological Relevance: Native Americans used plants from the genus Echinacea to treat a variety of different inflammatory conditions including swollen gums, sore throats, skin inflammation, and gastrointestinal disorders. Today, various...
5.
Secondary Metabolites from Fungal Endophytes of Suppress Cytokine Secretion by Macrophage-Type Cells
Kaur A, Oberhofer M, Juzumaite M, Raja H, Gulledge T, Kao D, et al.
Nat Prod Commun
. 2017 May;
11(8):1143-1146.
PMID: 28479944
Botanical extracts of have been widely used for the treatment of upper respiratory infections. We sought to chemically examine fungal endophytes inhabiting , and to identify compounds produced by these...
6.
Devlin A, Halvorsen P, Miller J, Laster S
Immunobiology
. 2017 Feb;
222(5):768-777.
PMID: 28237664
Leptospira interrogans (L. interrogans), the causative agent of leptospirosis, is a widespread zoonotic spirochete that lives a dual lifestyle. L. interrogans infects mice, rats, and wildlife in a persistent and...
7.
Moazami Y, Gulledge T, Laster S, Pierce J
Bioorg Med Chem Lett
. 2015 Jun;
25(16):3091-4.
PMID: 26105195
Alkylamides are lipophilic constituents of Echinacea and possess numerous biological activities. Although significant effort has been focused on the study of crude Echinacea extracts, very little is known regarding the...
8.
Todd D, Gulledge T, Britton E, Oberhofer M, Leyte-Lugo M, Moody A, et al.
PLoS One
. 2015 May;
10(5):e0124276.
PMID: 25933416
Echinacea preparations, which are used for the prevention and treatment of upper respiratory infections, account for 10% of the dietary supplement market in the U.S., with sales totaling more than...
9.
Pollara J, Spesock A, Pickup D, Laster S, Petty I
Virology
. 2012 Apr;
428(2):146-55.
PMID: 22534090
Prostaglandin E₂ (PGE₂) is an arachidonic acid (AA)-derived signaling molecule that can influence host immune responses to infection or vaccination. In this study, we investigated PGE₂ production in vitro by...
10.
Cecil C, Davis J, Cech N, Laster S
Int Immunopharmacol
. 2011 Jun;
11(11):1706-14.
PMID: 21683808
In this study we tested whether the isoquinoline alkaloid berberine can inhibit the growth of influenza A. Our experiments showed strong inhibition of the growth of H1N1 influenza A strains...