Scott M DeWire
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Explore the profile of Scott M DeWire including associated specialties, affiliations and a list of published articles.
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19
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2319
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Recent Articles
11.
DeWire S, Ahn S, Lefkowitz R, Shenoy S
Annu Rev Physiol
. 2007 Feb;
69:483-510.
PMID: 17305471
Upon their discovery, beta-arrestins 1 and 2 were named for their capacity to sterically hinder the G protein coupling of agonist-activated seven-transmembrane receptors, ultimately resulting in receptor desensitization. Surprisingly, recent...
12.
Violin J, DeWire S, Barnes W, Lefkowitz R
J Biol Chem
. 2006 Sep;
281(47):36411-9.
PMID: 17008309
Receptor desensitization progressively limits responsiveness of cells to chronically applied stimuli. Desensitization in the continuous presence of agonist has been difficult to study with available assay methods. Here, we used...
13.
Dittmer D, Gonzalez C, Vahrson W, DeWire S, Hines-Boykin R, Damania B
J Virol
. 2005 Jun;
79(13):8637-50.
PMID: 15956606
Rhesus monkey rhadinovirus (RRV) and Kaposi's sarcoma-associated herpesvirus (KSHV; also called human herpesvirus 8) belong to the gamma-2 grouping of herpesviruses. RRV and KSHV share a high degree of sequence...
14.
DeWire S, Damania B
J Virol
. 2005 Feb;
79(5):3127-38.
PMID: 15709032
Rhesus monkey rhadinovirus (RRV) is a gamma-2-herpesvirus that is closely related to Kaposi's sarcoma-associated herpesvirus/human herpesvirus-8. We have previously reported that the transcript for RRV latency-associated nuclear antigen (R-LANA) is...
15.
Damania B, Jeong J, Bowser B, DeWire S, Staudt M, Dittmer D
J Virol
. 2004 Apr;
78(10):5491-9.
PMID: 15113928
The viral immediate-early transactivator Rta/Orf50 is necessary and sufficient to initiate Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 (KSHV/HHV-8) reactivation from latently infected cells. Since Rta/Orf50 is conserved among all known gamma-2-herpesviruses,...
16.
Wang L, Wakisaka N, Tomlinson C, DeWire S, Krall S, Pagano J, et al.
Cancer Res
. 2004 Apr;
64(8):2774-81.
PMID: 15087393
Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) has been linked to Kaposi's sarcoma, primary effusion lymphoma, and multicentric Castleman's disease. In addition to endothelial cells and B lymphocytes, KSHV also has been shown...
17.
DeWire S, Money E, Krall S, Damania B
Virology
. 2003 Aug;
312(1):122-34.
PMID: 12890626
Rhesus monkey rhadinovirus (RRV) is a gamma-2-herpesvirus that is closely related to Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8). Lack of an efficient culture system to grow high titers of virus, and the...
18.
Bowser B, DeWire S, Damania B
J Virol
. 2002 Nov;
76(24):12574-83.
PMID: 12438583
The K1 protein of Kaposi's sarcoma-associated herpesvirus (KSHV) has been shown to be a transforming protein capable of inducing morphological changes and focus formation in rodent fibroblasts. K1 can activate...
19.
DeWire S, McVoy M, Damania B
J Virol
. 2002 Sep;
76(19):9819-31.
PMID: 12208960
Rhesus monkey rhadinovirus (RRV) is a close relative of Kaposi's sarcoma-associated herpesvirus (KSHV; human herpesvirus 8). RRV serves as an in vitro and an in vivo model for KSHV, and...