Scott L Pomeroy
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Explore the profile of Scott L Pomeroy including associated specialties, affiliations and a list of published articles.
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125
Citations
41647
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Recent Articles
21.
Clark A, Calligaris D, Regan M, Krummel D, Agar J, Kallay L, et al.
J Neurooncol
. 2018 Aug;
140(2):269-279.
PMID: 30128689
Purpose: Medulloblastoma, the most common primary pediatric malignant brain tumor, originates in the posterior fossa of the brain. Pineoblastoma, which originates within the pineal gland, is a rarer malignancy that...
22.
Waszak S, Northcott P, Buchhalter I, Robinson G, Sutter C, Groebner S, et al.
Lancet Oncol
. 2018 May;
19(6):785-798.
PMID: 29753700
Background: Medulloblastoma is associated with rare hereditary cancer predisposition syndromes; however, consensus medulloblastoma predisposition genes have not been defined and screening guidelines for genetic counselling and testing for paediatric patients...
23.
Archer T, Sengupta S, Pomeroy S
Handb Clin Neurol
. 2018 Feb;
148:785-797.
PMID: 29478614
Classically, brain cancers have been graded and diagnosed based on histology and risk stratified by clinical criteria. Recent advances in genomics and epigenomics have ushered in an era of defining...
24.
Northcott P, Buchhalter I, Morrissy A, Hovestadt V, Weischenfeldt J, Ehrenberger T, et al.
Nature
. 2017 Jul;
547(7663):311-317.
PMID: 28726821
Current therapies for medulloblastoma, a highly malignant childhood brain tumour, impose debilitating effects on the developing child, and highlight the need for molecularly targeted treatments with reduced toxicity. Previous studies...
25.
Wang B, Wu H, Chai C, Lewis J, Pichiorri F, Eisenstat D, et al.
Cancer Lett
. 2017 May;
401:20-32.
PMID: 28483517
The p53 protein plays a critical role in preventing tumor development. Although numerous factors have been shown to directly or indirectly regulate p53, the mechanism of how microRNAs (miRNAs) modulate...
26.
Archer T, Mahoney E, Pomeroy S
Neurotherapeutics
. 2017 Apr;
14(2):265-273.
PMID: 28386677
Recent advances in cancer genomics have revealed 4 distinct subgroups of medulloblastomas, each with unique transcription profiles, DNA alterations and clinical outcome. Molecular classification of medulloblastomas improves predictions of clinical...
27.
Boulay G, Awad M, Riggi N, Archer T, Iyer S, Boonseng W, et al.
Cancer Discov
. 2017 Feb;
7(3):288-301.
PMID: 28213356
Medulloblastoma is the most frequent malignant pediatric brain tumor and is divided into at least four subgroups known as WNT, SHH, Group 3, and Group 4. Here, we characterized gene...
28.
Poduri A, Pomeroy S
N Engl J Med
. 2016 Dec;
375(25):2494-2496.
PMID: 28002713
No abstract available.
29.
Wang X, Lee R, Alver B, Haswell J, Wang S, Mieczkowski J, et al.
Nat Genet
. 2016 Dec;
49(2):289-295.
PMID: 27941797
SMARCB1 (also known as SNF5, INI1, and BAF47), a core subunit of the SWI/SNF (BAF) chromatin-remodeling complex, is inactivated in nearly all pediatric rhabdoid tumors. These aggressive cancers are among...
30.