Scott C Farrow
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Explore the profile of Scott C Farrow including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
479
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Recent Articles
1.
Ginger M, Karnkowska A, Hampl V, Farrow S
Protist
. 2024 Sep;
175(6):126066.
PMID: 39288646
No abstract available.
2.
Aoki M, Kisiala A, Farrow S, Brunetti C, Huber R, Emery R
Biochem Biophys Rep
. 2024 Jul;
39:101756.
PMID: 38978539
Lonely guy (LOG) proteins are phosphoribohydrolases (PRHs) that are key cytokinin (CK)-activating enzymes in plant and non-plant CK-producing organisms. During CK biosynthesis, LOGs catalyze the conversion of precursor CK-nucleotides (CK-NTs)...
3.
Ebenezer T, Low R, ONeill E, Huang I, DeSimone A, Farrow S, et al.
Biol Open
. 2022 Nov;
11(11).
PMID: 36412269
Euglenoids (Euglenida) are unicellular flagellates possessing exceptionally wide geographical and ecological distribution. Euglenoids combine a biotechnological potential with a unique position in the eukaryotic tree of life. In large part...
4.
Shah M, Morrison E, Noble A, Farrow S
STAR Protoc
. 2022 Jan;
3(1):101043.
PMID: 34977684
is a source of high-value natural products. A major factor affecting consistent production of biomass is strain stability. Cryopreservation is a leading strategy for cell-line storage that helps ensure process...
5.
Uprety B, Morrison E, Emery R, Farrow S
Trends Biotechnol
. 2021 Oct;
40(4):482-508.
PMID: 34625276
To meet the growing demands of the oleochemical industry, tailored lipid sources are expanding to oleaginous microbes. To control the fatty acid composition of microbial lipids, ground-breaking exogenous and endogenous...
6.
Caputi L, Franke J, Bussey K, Farrow S, Curcino Vieira I, Stevenson C, et al.
Nat Chem Biol
. 2020 Feb;
16(4):383-386.
PMID: 32066966
Cycloaddition reactions generate chemical complexity in a single step. Here we report the crystal structures of three homologous plant-derived cyclases involved in the biosynthesis of iboga and aspidosperma alkaloids. These...
7.
Farrow S, Kamileen M, Caputi L, Bussey K, Mundy J, McAtee R, et al.
J Am Chem Soc
. 2019 Aug;
141(33):12979-12983.
PMID: 31364847
(-)-Ibogaine and (-)-voacangine are plant derived psychoactives that show promise as treatments for opioid addiction. However, these compounds are produced by hard to source plants, making these chemicals difficult for...
8.
Farrow S, Kamileen M, Meades J, Ameyaw B, Xiao Y, OConnor S
J Biol Chem
. 2018 Jul;
293(36):13821-13833.
PMID: 30030374
Monoterpenoid indole alkaloids are a large (∼3000 members) and structurally diverse class of metabolites restricted to a limited number of plant families in the order Gentianales. or iboga (Apocynaceae) is...
9.
Caputi L, Franke J, Farrow S, Chung K, Payne R, Nguyen T, et al.
Science
. 2018 May;
360(6394):1235-1239.
PMID: 29724909
Vinblastine, a potent anticancer drug, is produced by (Madagascar periwinkle) in small quantities, and heterologous reconstitution of vinblastine biosynthesis could provide an additional source of this drug. However, the chemistry...
10.
Hagel J, Morris J, Lee E, Desgagne-Penix I, Bross C, Chang L, et al.
BMC Plant Biol
. 2015 Sep;
15:227.
PMID: 26384972
Background: Benzylisoquinoline alkaloids (BIAs) represent a diverse class of plant specialized metabolites sharing a common biosynthetic origin beginning with tyrosine. Many BIAs have potent pharmacological activities, and plants accumulating them...