Scott B Vande Pol
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Explore the profile of Scott B Vande Pol including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
466
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Recent Articles
1.
Drews C, Brimer N, Vande Pol S
PLoS Pathog
. 2020 Jan;
16(1):e1008295.
PMID: 31971989
The HECT domain E3 ubiquitin ligase E6AP (UBE3A) is critical for the development of human papillomavirus (HPV) associated cancers, the neurodevelopment disorder Angelman Syndrome, and some cases of autism spectrum...
2.
Drews C, Case S, Vande Pol S
PLoS Pathog
. 2019 Apr;
15(4):e1007575.
PMID: 31002735
High-risk human papillomavirus (HPV) E6 proteins associate with the cellular ubiquitin ligase E6-Associated Protein (E6AP), and then recruit both p53 and certain cellular PDZ proteins for ubiquitination and degradation by...
3.
Strickland S, Brimer N, Lyons C, Vande Pol S
Virology
. 2018 Jan;
516:127-138.
PMID: 29346075
HPV E6 oncoproteins associate with cellular PDZ proteins. In addition to previously identified cellular PDZ proteins, we found association of the HPV16 E6 PBM with the Dystrophin Glycoprotein Complex, LRCC1,...
4.
Brimer N, Drews C, Vande Pol S
PLoS Pathog
. 2017 Dec;
13(12):e1006781.
PMID: 29281732
Papillomavirus E6 proteins bind to LXXLL peptide motifs displayed on targeted cellular proteins. Alpha genus HPV E6 proteins associate with the cellular ubiquitin ligase E6AP (UBE3A), by binding to an...
5.
Brimer N, Vande Pol S
J Virol
. 2013 Dec;
88(5):3027-30.
PMID: 24352452
Cancer-associated human papillomaviruses (HPVs) express E6 oncoproteins that target the degradation of p53 and have a carboxy-terminal PDZ ligand that is required for stable episomal maintenance of the HPV genome....
6.
Vande Pol S, Klingelhutz A
Virology
. 2013 May;
445(1-2):115-37.
PMID: 23711382
Papillomaviruses induce benign and malignant epithelial tumors, and the viral E6 oncoprotein is essential for full transformation. E6 contributes to transformation by associating with cellular proteins, docking on specific acidic...
7.
Ansari T, Brimer N, Vande Pol S
J Virol
. 2012 Aug;
86(20):11386-91.
PMID: 22896608
Human papillomavirus type 16 (HPV-16) E6 (16E6) binds the E3 ubiquitin ligase E6AP and p53, thereby targeting degradation of p53 (M. Scheffner, B. A. Werness, J. M. Huibregtse, A. J....
8.
Cooper B, Brimer N, Vande Pol S
J Virol
. 2007 Sep;
81(22):12675-9.
PMID: 17804489
The attachment and spreading of keratinocyte cells result from interactions between integrins and immobilized extracellular matrix molecules. Human papillomavirus type 16 (HPV-16) E6 augmented the kinetics of cell spreading, while...
9.
Bohl J, Brimer N, Lyons C, Vande Pol S
J Biol Chem
. 2007 Jan;
282(13):9392-9400.
PMID: 17237226
MPP7, a previously uncharacterized member of the p55 Stardust family of membrane-associated guanylate kinase (MAGUK) proteins, was found in a tripartite complex with DLG1 and LIN7A or LIN7C. MPP7 dimerizes...
10.
Jing M, Bohl J, Brimer N, Kinter M, Vande Pol S
J Virol
. 2006 Dec;
81(5):2231-9.
PMID: 17166906
Oncoproteins from DNA tumor viruses associate with critical cellular proteins to regulate cell proliferation, survival, and differentiation. Human papillomavirus (HPV) E6 oncoproteins have been previously shown to associate with a...