Scott B Hansen
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Explore the profile of Scott B Hansen including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Rangarajan E, Bois J, Hansen S, Izard T
Nat Commun
. 2024 Oct;
15(1):9270.
PMID: 39468080
Talin regulates crucial cellular functions, including cell adhesion and motility, and affects human diseases. Triggered by mechanical forces, talin plays crucial roles in facilitating the formation of focal adhesions and...
2.
Yuan Z, Pavel M, Hansen S
bioRxiv
. 2024 May;
PMID: 38746110
The γ-aminobutyric acid (GABA) type A receptor (GABAR), a GABA activated pentameric chloride channel, mediates fast inhibitory neurotransmission in the brain. The lipid environment is critical for GABAR function. How...
3.
Petersen E, Pavel M, Hansen S, Gudheti M, Wang H, Yuan Z, et al.
Elife
. 2024 Feb;
12.
PMID: 38407149
Rapid conversion of force into a biological signal enables living cells to respond to mechanical forces in their environment. The force is believed to initially affect the plasma membrane and...
4.
Call I, Bois J, Hansen S
bioRxiv
. 2023 Oct;
PMID: 37873307
The plasma membrane is a well-organized structure of lipids and proteins, segmented into lipid compartments under 200 nm in size. This specific spatial patterning is crucial for the function of...
5.
Hansen S
J Alzheimers Dis
. 2023 Jul;
94(2):471-472.
PMID: 37393509
Alzheimer's disease (AD) is a neurodegenerative disorder associated with neuroinflammation and altered lipids in the brain. Cholesterol is a key component of inflammatory lipids. However, the role of cholesterol in...
6.
Hansen S, Wang H
Pharmacol Ther
. 2023 Jun;
249:108486.
PMID: 37390970
Neurodegeneration and its loss of cognitive function is associated with inflammation and an accumulation of lipids. In the periphery, cholesterol's uptake drives a major component of chronic inflammation. In this...
7.
Wing P, Schmidt N, Peters R, Erdmann M, Brown R, Wang H, et al.
PLoS Pathog
. 2023 May;
19(5):e1011323.
PMID: 37134108
The severity of disease following infection with SARS-CoV-2 is determined by viral replication kinetics and host immunity, with early T cell responses and/or suppression of viraemia driving a favourable outcome....
8.
Wang H, Yuan Z, Pavel M, Jablonski S, Jablonski J, Hobson R, et al.
J Biol Chem
. 2023 Apr;
299(6):104763.
PMID: 37119851
Coronavirus disease 2019 (COVID-19) is a respiratory infection caused by severe acute respiratory syndrome coronavirus 2. The virus binds to angiotensinogen converting enzyme 2 (ACE2), which mediates viral entry into...
9.
Hansen S, Yuan Z
Cell Chem Biol
. 2023 Mar;
30(3):233-234.
PMID: 36931249
In this issue of Cell Chemical Biology, Miao et al. develop probes for live cell tracking of SARS-CoV-2. The probes reveal the endocytic pathway for viral entry. Unexpectedly, the antiviral...
10.
Yuan Z, Hansen S
Membranes (Basel)
. 2023 Feb;
13(2).
PMID: 36837753
Cholesterol and phosphatidyl inositol 4,5-bisphosphate (PIP) are hydrophobic molecules that regulate protein function in the plasma membrane of all cells. In this review, we discuss how changes in cholesterol concentration...