Scot Federman
Overview
Explore the profile of Scot Federman including associated specialties, affiliations and a list of published articles.
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54
Citations
4378
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Recent Articles
1.
Vasudevan H, Lazar A, Reyes K, Rong D, Arevalo S, Federman S, et al.
Anticancer Res
. 2024 Dec;
44(12):5445-5453.
PMID: 39626922
Background/aim: Plasma Epstein-Barr virus (EBV) viral load measurement is prognostic in nasopharyngeal carcinoma (NPC) disease monitoring; however, a consensus measurement approach does not exist. This study characterized the clinical performance...
2.
Loeb G, Kathail P, Shuai R, Chung R, Grona R, Peddada S, et al.
Nat Genet
. 2024 Sep;
56(10):2078-2092.
PMID: 39256582
Kidney failure, the decrease of kidney function below a threshold necessary to support life, is a major cause of morbidity and mortality. We performed a genome-wide association study (GWAS) of...
3.
Loeb G, Kathail P, Shuai R, Chung R, Grona R, Peddada S, et al.
bioRxiv
. 2024 Jul;
PMID: 38948875
Kidney disease is highly heritable; however, the causal genetic variants, the cell types in which these variants function, and the molecular mechanisms underlying kidney disease remain largely unknown. To identify...
4.
Heo S, Enriquez L, Federman S, Chang A, Mace R, Shevade K, et al.
Genome Biol
. 2024 Jan;
25(1):25.
PMID: 38243310
CRISPR genome editing approaches theoretically enable researchers to define the function of each human gene in specific cell types, but challenges remain to efficiently perform genetic perturbations in relevant models....
5.
Orf G, Olivo A, Harris B, Weiss S, Achari A, Yu G, et al.
Viruses
. 2023 Apr;
15(4).
PMID: 37113001
Metagenomic next-generation sequencing (mNGS) has enabled the high-throughput multiplexed identification of sequences from microbes of potential medical relevance. This approach has become indispensable for viral pathogen discovery and broad-based surveillance...
6.
Orf G, Perez L, Meyer T, Luk K, Forberg K, Rodgers M, et al.
Virus Evol
. 2023 Apr;
9(1):vead018.
PMID: 37025159
Pathogens carried by insects, such as bunyaviruses, are frequently transmitted into human populations and cause diseases. Knowing which spillover events represent a public health threat remains a challenge. Metagenomic next-generation...
7.
Walters W, Granados A, Ley C, Federman S, Stryke D, Santos Y, et al.
Cell Host Microbe
. 2023 Feb;
31(2):187-198.e3.
PMID: 36758519
The human gut virome and its early life development are poorly understood. Prior studies have captured single-point assessments with the evolution of the infant virome remaining largely unexplored. We performed...
8.
Gu W, Rauschecker A, Hsu E, Zorn K, Sucu Y, Federman S, et al.
JAMA Neurol
. 2021 Sep;
78(11):1355-1366.
PMID: 34515766
Importance: Cerebrospinal fluid (CSF) cytologic testing and flow cytometry are insensitive for diagnosing neoplasms of the central nervous system (CNS). Such clinical phenotypes can mimic infectious and autoimmune causes of...
9.
Gu W, Talevich E, Hsu E, Qi Z, Urisman A, Federman S, et al.
Genome Med
. 2021 Jun;
13(1):98.
PMID: 34074327
Background: Metagenomic next-generation sequencing (mNGS) of body fluids is an emerging approach to identify occult pathogens in undiagnosed patients. We hypothesized that metagenomic testing can be simultaneously used to detect...
10.
Deng X, Garcia-Knight M, Khalid M, Servellita V, Wang C, Morris M, et al.
Cell
. 2021 May;
184(13):3426-3437.e8.
PMID: 33991487
We identified an emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant by viral whole-genome sequencing of 2,172 nasal/nasopharyngeal swab samples from 44 counties in California, a state in the...