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Sayo Horibe

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Articles 21
Citations 300
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Recent Articles
1.
Krisnanda A, Sasaki N, Ito K, Tanaka T, Shinohara M, Amin H, et al.
Kobe J Med Sci . 2025 Feb; 70(4):E130-E142. PMID: 39993786
Aim: Our previous studies identified ultraviolet B (UVB) irradiation as a possible approach for preventing atherosclerosis. The aim of this study was to clarify the effect of 312 nm UVB,...
2.
Tanaka T, Sasaki N, Krisnanda A, Shinohara M, Amin H, Horibe S, et al.
J Am Heart Assoc . 2024 Jan; 13(2):e031639. PMID: 38214259
Background: Ultraviolet B (UV-B) irradiation is an effective treatment for human cutaneous disorders and was shown to reduce experimental atherosclerosis by attenuating immunoinflammatory responses. The aim of this study was...
3.
Horibe S, Emoto T, Mizoguchi T, Tanaka T, Kawauchi S, Sasaki N, et al.
Glia . 2023 Aug; 72(1):51-68. PMID: 37610154
Alzheimer's disease (AD) is among the most prevalent age-related neurodegenerative diseases. Endothelial cell (EC) senescence was discovered in the AD brain, but its function in AD pathogenesis was unidentified. Here...
4.
Kawauchi S, Mizoguchi T, Horibe S, Tanaka T, Sasaki N, Ikeda K, et al.
Glia . 2022 Oct; 71(2):467-479. PMID: 36286494
In the brain, neurons, glial cells, vascular endothelial cells (ECs), and mural cells form a functional structure referred to as the neurovascular unit (NVU). The functions of the NVU become...
5.
Kasahara K, Sasaki N, Amin H, Tanaka T, Horibe S, Yamashita T, et al.
Heliyon . 2022 Jul; 8(7):e09981. PMID: 35898604
Compelling evidence suggests a crucial role for Foxp3 regulatory T cells (Tregs) in the control of atherosclerosis. Although suppression of pro-inflammatory CD4 T cell immune responses is supposed to be...
6.
Horibe S, Ishikawa K, Nakada K, Wake M, Takeda N, Tanaka T, et al.
Oncol Rep . 2021 Dec; 47(2). PMID: 34935060
The efficacy of cisplatin (CDDP) has been demonstrated in the treatment of various cancers as monotherapy and combination therapy with immunotherapy. However, acquired CDDP resistance is a major obstacle to...
7.
Amin H, Sasaki N, Yamashita T, Mizoguchi T, Hayashi T, Emoto T, et al.
Sci Rep . 2019 Jun; 9(1):8065. PMID: 31147569
Vascular inflammation via T-cell-mediated immune responses has been shown to be critically involved in the pathogenesis of abdominal aortic aneurysm (AAA). T-cell coinhibitory molecule cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) is known...
8.
Kawauchi S, Horibe S, Sasaki N, Tanahashi T, Mizuno S, Hamaguchi T, et al.
Mar Drugs . 2019 Feb; 17(2). PMID: 30744124
Nonalcoholic steatohepatitis (NASH) progresses from nonalcoholic fatty liver disease (NAFLD); however, efficacious drugs for NASH treatment are lacking. Sodium alginate (SA), a soluble dietary fiber extracted from brown algae, could...
9.
Kawauchi S, Horibe S, Sasaki N, Hirata K, Rikitake Y
Exp Cell Res . 2018 Dec; 374(2):333-341. PMID: 30553966
Here, we developed a novel in vitro co-culture model, in which process-bearing astrocytes and isolated cerebral microvessels from mice were co-cultured. Astrocytes formed contacts with microvessels from both adult and...
10.
Horibe S, Kawauchi S, Tanahashi T, Sasaki N, Mizuno S, Rikitake Y
Biochem Biophys Res Commun . 2018 Nov; 507(1-4):426-432. PMID: 30448176
Cisplatin (CDDP) is widely used as an anti-cancer platinum agent but its therapeutic efficacy is limited by acquired drug resistance. To develop a new therapeutic strategy that could overcome this...