Shoji Kawauchi
Overview
Explore the profile of Shoji Kawauchi including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
321
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Recent Articles
1.
Horibe S, Emoto T, Mizoguchi T, Tanaka T, Kawauchi S, Sasaki N, et al.
Glia
. 2023 Aug;
72(1):51-68.
PMID: 37610154
Alzheimer's disease (AD) is among the most prevalent age-related neurodegenerative diseases. Endothelial cell (EC) senescence was discovered in the AD brain, but its function in AD pathogenesis was unidentified. Here...
2.
Kawauchi S, Mizoguchi T, Horibe S, Tanaka T, Sasaki N, Ikeda K, et al.
Glia
. 2022 Oct;
71(2):467-479.
PMID: 36286494
In the brain, neurons, glial cells, vascular endothelial cells (ECs), and mural cells form a functional structure referred to as the neurovascular unit (NVU). The functions of the NVU become...
3.
Horibe S, Ishikawa K, Nakada K, Wake M, Takeda N, Tanaka T, et al.
Oncol Rep
. 2021 Dec;
47(2).
PMID: 34935060
The efficacy of cisplatin (CDDP) has been demonstrated in the treatment of various cancers as monotherapy and combination therapy with immunotherapy. However, acquired CDDP resistance is a major obstacle to...
4.
Amin H, Sasaki N, Yamashita T, Mizoguchi T, Hayashi T, Emoto T, et al.
Sci Rep
. 2019 Jun;
9(1):8065.
PMID: 31147569
Vascular inflammation via T-cell-mediated immune responses has been shown to be critically involved in the pathogenesis of abdominal aortic aneurysm (AAA). T-cell coinhibitory molecule cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) is known...
5.
Kawauchi S, Horibe S, Sasaki N, Tanahashi T, Mizuno S, Hamaguchi T, et al.
Mar Drugs
. 2019 Feb;
17(2).
PMID: 30744124
Nonalcoholic steatohepatitis (NASH) progresses from nonalcoholic fatty liver disease (NAFLD); however, efficacious drugs for NASH treatment are lacking. Sodium alginate (SA), a soluble dietary fiber extracted from brown algae, could...
6.
Kawauchi S, Horibe S, Sasaki N, Hirata K, Rikitake Y
Exp Cell Res
. 2018 Dec;
374(2):333-341.
PMID: 30553966
Here, we developed a novel in vitro co-culture model, in which process-bearing astrocytes and isolated cerebral microvessels from mice were co-cultured. Astrocytes formed contacts with microvessels from both adult and...
7.
Horibe S, Kawauchi S, Tanahashi T, Sasaki N, Mizuno S, Rikitake Y
Biochem Biophys Res Commun
. 2018 Nov;
507(1-4):426-432.
PMID: 30448176
Cisplatin (CDDP) is widely used as an anti-cancer platinum agent but its therapeutic efficacy is limited by acquired drug resistance. To develop a new therapeutic strategy that could overcome this...
8.
Kawauchi S, Wada K, Oita A
Int J Clin Pharmacol Ther
. 2018 Sep;
57(1):32-36.
PMID: 30220292
Objective: Prior to heart transplant, sensitization to human leukocyte antigen can occur after blood transfusions used during implantation of ventricular assist devices. The result is an increased risk of antibody-mediated...
9.
Sato J, Horibe S, Kawauchi S, Sasaki N, Hirata K, Rikitake Y
J Neurochem
. 2018 Jul;
147(4):495-513.
PMID: 29981530
In the central nervous system, astrocytes extend endfoot processes to ensheath synapses and microvessels. However, the mechanisms underlying this astrocytic process extension remain unclear. A limitation of the use of...
10.
Horibe S, Tanahashi T, Kawauchi S, Murakami Y, Rikitake Y
BMC Cancer
. 2018 Jan;
18(1):47.
PMID: 29306323
Background: Exosomes, small-membrane vesicles, are secreted by cells and include several types of proteins and nucleic acids. Exosomes transfer cellular information derived from donor cells and are involved in various...