Saumyendra N Sarkar
Overview
Explore the profile of Saumyendra N Sarkar including associated specialties, affiliations and a list of published articles.
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18
Citations
401
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Recent Articles
1.
Sarkar S, Corbin D, Simpkins J
Pharmaceuticals (Basel)
. 2024 Mar;
17(3).
PMID: 38543056
The bottleneck in drug discovery for central nervous system diseases is the absence of effective systemic drug delivery technology for delivering therapeutic drugs into the brain. Despite the advances in...
2.
Quintana D, Anantula Y, Garcia J, Engler-Chiurazzi E, Sarkar S, Corbin D, et al.
Neurobiol Aging
. 2021 Jun;
105:115-128.
PMID: 34062487
Heart disease and vascular disease positively correlate with the incidence of Alzheimer's disease (AD). Although there is ostensible involvement of dysfunctional cerebrovasculature in AD pathophysiology, the characterization of the specific...
3.
Kim S, Russell A, Wang W, Gemoets D, Sarkar S, Simpkins J, et al.
J Neuroimmune Pharmacol
. 2021 May;
17(1-2):228-241.
PMID: 34028667
Alzheimer's disease (AD) and other neurodegenerative diseases are characterized by chronic neuroinflammation and a reduction in brain energy metabolism. An important role has emerged for small, non-coding RNA molecules known...
4.
Porter K, Sarkar S, Dakhlallah D, Vannoy M, Quintana D, Simpkins J
Front Aging Neurosci
. 2020 Apr;
12:92.
PMID: 32317959
Despite the extensive use of hormonal methods as either contraception or menopausal hormone therapy (HT), there is very little known about the potential effects of these compounds on the cellular...
5.
Quintana D, Garcia J, Anantula Y, Rellick S, Engler-Chiurazzi E, Sarkar S, et al.
J Alzheimers Dis
. 2020 Apr;
75(1):119-138.
PMID: 32250296
Cerebrovascular pathology is pervasive in Alzheimer's disease (AD), yet it is unknown whether cerebrovascular dysfunction contributes to the progression or etiology of AD. In human subjects and in animal models...
6.
Hu H, Hone E, Provencher E, Sprowls S, Farooqi I, Corbin D, et al.
Sci Rep
. 2020 Feb;
10(1):3233.
PMID: 32094435
Blood-brain barrier (BBB) dysfunction occurs in cerebrovascular diseases and neurodegenerative disorders such as stroke. Opening of the BBB during a stroke has a negative impact on acute outcomes. We have...
7.
Cavendish J, Sarkar S, Colantonio M, Quintana D, Ahmed N, White B, et al.
J Alzheimers Dis
. 2019 Jun;
70(1):139-151.
PMID: 31177221
Mitochondrial dysfunction is often found in Alzheimer's disease (AD) patients and animal models. Clinical severity of AD is linked to early deficiencies in cognitive function and brain metabolism, indicating that...
8.
Sarkar S, Russell A, Engler-Chiurazzi E, Porter K, Simpkins J
Aging Dis
. 2019 Apr;
10(2):329-352.
PMID: 31011481
Aging is a complex and integrated gradual deterioration of cellular activities in specific organs of the body, which is associated with increased mortality. This deterioration is the primary risk factor...
9.
Quintana D, Garcia J, Sarkar S, Jun S, Engler-Chiurazzi E, Russell A, et al.
Mitochondrion
. 2018 Dec;
47:244-255.
PMID: 30594729
Astrocytes serve to maintain proper neuronal function and support neuronal viability, but remain largely understudied in research of cerebral ischemia. Astrocytic mitochondria are core participants in the metabolic activity of...
10.
Ren X, Engler-Chiurazzi E, Russell A, Sarkar S, Rellick S, Lewis S, et al.
Neurochem Int
. 2018 Oct;
127:73-79.
PMID: 30365981
Aging of the nervous system, and the occurrence of age-related brain diseases such as stroke, are associated with changes to a variety of cellular processes controlled by many distinct genes....