Saul Carcamo
Overview
Explore the profile of Saul Carcamo including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
293
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Recent Articles
1.
Karakose E, Wang X, Wang P, Carcamo S, Demircioglu D, Lambertini L, et al.
Cell Rep Med
. 2024 Dec;
5(12):101832.
PMID: 39626675
Diabetes results from an inadequate number of insulin-producing human beta cells. There is currently no clinically available effective means to restore beta cell mass in millions of people with diabetes....
2.
Sango J, Carcamo S, Sirenko M, Maiti A, Mansour H, Ulukaya G, et al.
Nature
. 2024 Oct;
636(8041):241-250.
PMID: 39478230
Cancer driver mutations often show distinct temporal acquisition patterns, but the biological basis for this, if any, remains unknown. RAS mutations occur invariably late in the course of acute myeloid...
3.
Grossi E, Nguyen C, Carcamo S, Moran S, Callau V, Filipescu D, et al.
bioRxiv
. 2024 Sep;
PMID: 39229151
Multimeric SWI/SNF chromatin remodelers assemble into discrete conformations with unique complex functionalities difficult to dissect. Distinct cancers harbor mutations in specific subunits, altering the chromatin landscape, such as the PBAF-specific...
4.
Proteau S, Krossa I, Husser C, Gueguinou M, Sella F, Bille K, et al.
EMBO Mol Med
. 2024 Aug;
16(9):2262-2267.
PMID: 39164473
No abstract available.
5.
Jostes S, Vardabasso C, Dong J, Carcamo S, Singh R, Phelps R, et al.
Genes Dev
. 2024 May;
38(7-8):336-353.
PMID: 38744503
High levels of H2A.Z promote melanoma cell proliferation and correlate with poor prognosis. However, the role of the two distinct H2A.Z histone chaperone complexes SRCAP and P400-TIP60 in melanoma remains...
6.
Jostes S, Vardabasso C, Dong J, Carcamo S, Singh R, Phelps R, et al.
bioRxiv
. 2023 Dec;
PMID: 38076914
High levels of H2A.Z promote melanoma cell proliferation and correlate with poor prognosis. However, the role of the two distinct H2A.Z histone chaperone complexes, SRCAP and P400-TIP60, in melanoma remains...
7.
LKB1-SIK2 loss drives uveal melanoma proliferation and hypersensitivity to SLC8A1 and ROS inhibition
Proteau S, Krossa I, Husser C, Gueguinou M, Sella F, Bille K, et al.
EMBO Mol Med
. 2023 Nov;
15(12):e17719.
PMID: 37966164
Metastatic uveal melanomas are highly resistant to all existing treatments. To address this critical issue, we performed a kinome-wide CRISPR-Cas9 knockout screen, which revealed the LKB1-SIK2 module in restraining uveal...
8.
Efe G, Dunbar K, Sugiura K, Cunningham K, Carcamo S, Karaiskos S, et al.
Cancer Discov
. 2023 Sep;
13(12):2632-2651.
PMID: 37676642
Significance: The invasion-metastasis cascade is a recalcitrant barrier to effective cancer therapy. We establish that the p53-R172H-dependent BRD4-CSF-1 axis is a mediator of prometastatic properties, correlates with patient survival and...
9.
Filipescu D, Carcamo S, Agarwal A, Tung N, Humblin E, Goldberg M, et al.
Nat Cell Biol
. 2023 Aug;
25(9):1332-1345.
PMID: 37605008
MacroH2A has established tumour suppressive functions in melanoma and other cancers, but an unappreciated role in the tumour microenvironment. Using an autochthonous, immunocompetent mouse model of melanoma, we demonstrate that...
10.
Singh D, Carcamo S, Farias E, Hasson D, Zheng W, Sun D, et al.
Cell Rep
. 2023 Jun;
42(6):112560.
PMID: 37267946
Disseminated cancer cells (DCCs) in secondary organs can remain dormant for years to decades before reactivating into overt metastasis. Microenvironmental signals leading to cancer cell chromatin remodeling and transcriptional reprogramming...