Satyaprakash Nayak
Overview
Explore the profile of Satyaprakash Nayak including associated specialties, affiliations and a list of published articles.
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19
Citations
176
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Recent Articles
11.
Nayak S, Sander O, Al-Huniti N, de Alwis D, Chain A, Chenel M, et al.
Clin Pharmacol Ther
. 2018 Jan;
103(3):378-383.
PMID: 29330855
Quantitative pharmacology (QP) applications in translational medicine, drug-development, and therapeutic use were crowd-sourced by the ASCPT Impact and Influence initiative. Highlighted QP case studies demonstrated faster access to innovative therapies...
12.
Rogers K, Bhattacharya I, Martin S, Nayak S
Clin Transl Sci
. 2017 Oct;
11(1):4-7.
PMID: 28986961
No abstract available.
13.
Sandborn W, Lee S, Tarabar D, Louis E, Klopocka M, Klaus J, et al.
Gut
. 2017 Oct;
67(10):1824-1835.
PMID: 28982740
Objective: This phase II, randomised, double-blind, placebo-controlled clinical trial was designed to evaluate the efficacy and safety of PF-00547659, a fully human monoclonal antibody that binds to human mucosal addressin...
14.
Hassan-Zahraee M, Banerjee A, Cheng J, Zhang W, Ahmad A, Page K, et al.
J Crohns Colitis
. 2017 Sep;
12(1):77-86.
PMID: 28961803
Objective: To define pharmacodynamic biomarkers in the peripheral blood of patients with Crohn's disease [CD] after treatment with PF-00547659, an anti-human mucosal addressin cell adhesion molecule-1 [MAdCAM-1] monoclonal antibody. Methods:...
15.
Hickling T, Chen X, Vicini P, Nayak S
J Pharmacokinet Pharmacodyn
. 2014 Oct;
41(5):445-59.
PMID: 25326873
A key role of B cells in the mammalian immune response is the generation of antibodies that serve to protect the organism against antigenic challenges. The same process may also...
16.
Lequieu J, Chakrabarti A, Nayak S, Varner J
PLoS Comput Biol
. 2011 Nov;
7(11):e1002263.
PMID: 22102801
Insulin, the primary hormone regulating the level of glucose in the bloodstream, modulates a variety of cellular and enzymatic processes in normal and diseased cells. Insulin signals are processed by...
17.
Tasseff R, Nayak S, Song S, Yen A, Varner J
Integr Biol (Camb)
. 2011 Mar;
3(5):578-91.
PMID: 21437295
Manipulation of differentiation programs has therapeutic potential in a spectrum of human cancers and neurodegenerative disorders. In this study, we integrated computational and experimental methods to unravel the response of...
18.
Nayak S, Shen M, Bunaciu R, Bloom S, Varner J, Yen A
Leuk Lymphoma
. 2010 Jul;
51(9):1734-47.
PMID: 20615082
Arsenic trioxide (ATO) synergistically promotes all trans retinoic acid (ATRA)-induced differentiation of PML-RARalpha negative HL-60 myeloblastic leukemia cells. In PML-RARalpha positive myeloid leukemia cells, ATO is known to cause degradation...
19.
Tasseff R, Nayak S, Salim S, Kaushik P, Rizvi N, Varner J
PLoS One
. 2010 Feb;
5(1):e8864.
PMID: 20126616
Androgen ablation therapy is currently the primary treatment for metastatic prostate cancer. Unfortunately, in nearly all cases, androgen ablation fails to permanently arrest cancer progression. As androgens like testosterone are...
20.
Nayak S, Salim S, Luan D, Zai M, Varner J
PLoS One
. 2008 Apr;
3(4):e2016.
PMID: 18431497
Robustness, a long-recognized property of living systems, allows function in the face of uncertainty while fragility, i.e., extreme sensitivity, can potentially lead to catastrophic failure following seemingly innocuous perturbations. Carlson...