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Sathish K Murali

Explore the profile of Sathish K Murali including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 182
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Recent Articles
1.
Poulsen S, Murali S, Thomas L, Assmus A, Rosenbaek L, Nielsen R, et al.
Kidney Int . 2024 Aug; 107(2):280-295. PMID: 39089578
The sodium/proton exchanger-3 (NHE3) plays a major role in acid-base and extracellular volume regulation and is also implicated in calcium homeostasis. As calcium and phosphate balances are closely linked, we...
2.
Murali S, McCormick J, Fenton R
Am J Physiol Renal Physiol . 2024 Mar; 326(5):F814-F826. PMID: 38545647
Aquaporin 2 (AQP2) is a vasopressin (VP)-regulated water channel in the renal collecting duct. Phosphorylation and ubiquitylation of AQP2 play an essential role in controlling the cellular abundance of AQP2...
3.
Little R, Murali S, Poulsen S, Grimm P, Assmus A, Cheng L, et al.
JCI Insight . 2023 Jan; 8(5). PMID: 36719746
Dietary potassium (K+) supplementation is associated with a lowering effect in blood pressure (BP), but not all studies agree. Here, we examined the effects of short- and long-term K+ supplementation...
4.
Rosenbaek L, Petrillo F, van Bemmelen M, Staub O, Murali S, Fenton R
Front Physiol . 2022 Sep; 13:971251. PMID: 36160843
Na and K balance is influenced by the activity of the sodium chloride cotransporter NCC in the distal convoluted tubule. NCC activity and abundance are reduced by high extracellular K....
5.
Murali S, Little R, Poulsen S, Ferdaus M, Ellison D, McCormick J, et al.
Cells . 2022 Jan; 11(1). PMID: 35011657
The thiazide-sensitive sodium chloride cotransporter (NCC) plays a vital role in maintaining sodium (Na) and potassium (K) homeostasis. NCC activity is modulated by with-no-lysine kinases 1 and 4 (WNK1 and...
6.
Aroankins T, Murali S, Fenton R, Wu Q
Front Mol Biosci . 2021 Dec; 8:790606. PMID: 34881291
Protein post-translational modification by the Small Ubiquitin-like MOdifier (SUMO) on lysine residues is a reversible process highly important for transcription and protein stability. In the kidney, SUMOylation appears to be...
7.
Wu Q, Poulsen S, Murali S, Grimm P, Su X, Delpire E, et al.
J Am Soc Nephrol . 2021 Jul; 32(9):2195-2209. PMID: 34230103
Background: Urinary extracellular vesicles (uEVs) are secreted into urine by cells from the kidneys and urinary tract. Although changes in uEV proteins are used for quantitative assessment of protein levels...
8.
Kortenoeven M, Esteva-Font C, Dimke H, Poulsen S, Murali S, Fenton R
J Biol Chem . 2021 Jun; 297(2):100915. PMID: 34174287
The thiazide-sensitive sodium-chloride cotransporter (NCC) in the renal distal convoluted tubule (DCT) plays a critical role in regulating blood pressure (BP) and K homeostasis. During hyperkalemia, reduced NCC phosphorylation and...
9.
Poulsen S, Cheng L, Penton D, Kortenoeven M, Matchkov V, Loffing J, et al.
Kidney Int . 2021 May; 100(2):321-335. PMID: 33940111
The thiazide-sensitive sodium-chloride-cotransporter (NCC) in the kidney distal convoluted tubule (DCT) plays an essential role in sodium and potassium homeostasis. Here, we demonstrate that NCC activity is increased by the...
10.
Fenton R, Murali S, Moeller H
Am J Physiol Cell Physiol . 2020 May; 319(1):C1-C10. PMID: 32432927
In mammals, conservation of body water is critical for survival and is dependent on the kidneys' ability to minimize water loss in the urine during periods of water deprivation. The...