Sarthak Gupta
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Explore the profile of Sarthak Gupta including associated specialties, affiliations and a list of published articles.
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60
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1490
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Recent Articles
1.
Sagar B, Gupta S, Verma S, Manohara Reddy Y, Shukla S
Eur J Med Chem
. 2024 Dec;
283():117131.
PMID: 39647418
Cancer treatment is a formidable challenge due to the adverse effects associated with non-selective therapies like chemotherapy and radiotherapy. This review article primarily centers on the application of Peptide-Drug Conjugates...
2.
Krishna H, Gaur R, Gupta S, Ghatak S
Anat Cell Biol
. 2024 Nov;
PMID: 39592264
During routine dissection, we observed a unique case of unilateral polydactyly in the left foot of a 61-year-old male cadaver. We observed the medial head of the quadratus plantae (QP)...
3.
Gupta S, Swoger M, Saldanha R, Schwarz J, Patteson A
Curr Opin Cell Biol
. 2024 Aug;
90:102408.
PMID: 39121805
Biologists have the capability to edit a genome at the nanometer scale and then observe whether or not the edit affects the structure of a developing organ or organism at...
4.
Patino-Martinez E, Nakabo S, Jiang K, Carmona-Rivera C, Tsai W, Claybaugh D, et al.
J Immunol
. 2024 Jul;
213(4):419-434.
PMID: 38949522
The Krebs cycle enzyme aconitate decarboxylase 1 (ACOD1) mediates itaconate synthesis in monocytes and macrophages. Previously, we reported that administration of 4-octyl itaconate to lupus-prone mice abrogated immune dysregulation and...
5.
Oliveira C, Temesgen-Oyelakin Y, Naqi M, Davis M, Naz F, DellOrso S, et al.
Arthritis Rheumatol
. 2024 Jun;
76(10):1501-1511.
PMID: 38923259
Objective: Systemic lupus erythematosus (SLE) increases cardiovascular disease (CVD) risk, and this is not explained by traditional risk factors. Characterization of blood immunologic signatures that associate with subclinical CVD and...
6.
Gupta S, Yamada E, Nakamura H, Perez P, Pranzatelli T, Dominick K, et al.
Ann Rheum Dis
. 2024 Mar;
83(8):1034-1047.
PMID: 38527764
Objectives: Inflammatory cytokines that signal through the Janus kinases-signal transducer and activator of transcription (JAK-STAT) pathway, especially interferons (IFNs), are implicated in Sjögren's disease (SjD). Although inhibition of JAKs is...
7.
Pranzatelli T, Perez P, Ku A, Matuck B, Huynh K, Sakai S, et al.
Res Sq
. 2024 Jan;
PMID: 38196575
Sjögren's Disease (SjD) is a systemic autoimmune disease without a clear etiology or effective therapy. Utilizing unbiased single-cell and spatial transcriptomics to analyze human minor salivary glands in health and...
8.
Nakabo S, Kaplan M, Gupta S
J Vis Exp
. 2023 Dec;
(202).
PMID: 38108450
Neutrophils are myeloid-lineage cells that form a crucial part of the innate immune system. The past decade has revealed additional key roles that neutrophils play in the pathogenesis of cancer,...
9.
Asp M, Jutzeler E, Kochanowski J, Kerr K, Song D, Gupta S, et al.
Biophysicist (Rockv)
. 2023 Dec;
3(2):94-105.
PMID: 38098945
Rheology and the study of viscoelastic materials are an integral part of engineering and the study of biophysical systems. Tissue rheology is even used in the study of cancer and...
10.
Berg I, Currey M, Gupta S, Berrada Y, Nguyen B, Pho M, et al.
J Cell Sci
. 2023 Sep;
136(20).
PMID: 37756607
Chromatin plays an essential role in the nuclear mechanical response and determining nuclear shape, which maintain nuclear compartmentalization and function. However, major genomic functions, such as transcription activity, might also...