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Sari E Jalkanen

Explore the profile of Sari E Jalkanen including associated specialties, affiliations and a list of published articles. Areas
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Citations 397
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Recent Articles
1.
Jalkanen S, Lahesmaa-Korpinen A, Heckman C, Rantanen V, Porkka K, Hautaniemi S, et al.
Exp Hematol . 2012 Jun; 40(9):705-714.e3. PMID: 22659387
Tyrosine kinase inhibitors (TKIs) have dramatically improved treatment outcomes in chronic myeloid leukemia (CML), but a proportion of patients fail to achieve optimal molecular response. By using a phosphoproteomic approach,...
2.
Koskela H, Eldfors S, Ellonen P, van Adrichem A, Kuusanmaki H, Andersson E, et al.
N Engl J Med . 2012 May; 366(20):1905-13. PMID: 22591296
Background: T-cell large granular lymphocytic leukemia is a rare lymphoproliferative disorder characterized by the expansion of clonal CD3+CD8+ cytotoxic T lymphocytes (CTLs) and often associated with autoimmune disorders and immune-mediated...
3.
Jalkanen S, Vakkila J, Kreutzman A, Nieminen J, Porkka K, Mustjoki S
Exp Hematol . 2010 Sep; 39(1):102-113.e1. PMID: 20869423
Objective: In chronic myeloid leukemia (CML), uncontrolled tyrosine kinase activity of the BCR-ABL1 oncoprotein results in aberrant signaling pathways and increased cell proliferation. Acquired immune tolerance to leukemic antigens further...